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Bifurcation drives the evolution of assembly-line biosynthesis.
Booth TJ, Bozhüyük KAJ, Liston JD, Batey SFD, Lacey E, Wilkinson B. Booth TJ, et al. Among authors: liston jd. Nat Commun. 2022 Jun 17;13(1):3498. doi: 10.1038/s41467-022-30950-z. Nat Commun. 2022. PMID: 35715397 Free PMC article.
The catechol moiety of obafluorin is essential for antibacterial activity.
Batey SFD, Davie MJ, Hems ES, Liston JD, Scott TA, Alt S, Francklyn CS, Wilkinson B. Batey SFD, et al. Among authors: liston jd. RSC Chem Biol. 2023 Aug 21;4(11):926-941. doi: 10.1039/d3cb00127j. eCollection 2023 Nov 1. RSC Chem Biol. 2023. PMID: 37920400 Free PMC article.