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SPR741, an Antibiotic Adjuvant, Potentiates the In Vitro and In Vivo Activity of Rifampin against Clinically Relevant Extensively Drug-Resistant Acinetobacter baumannii.
Zurawski DV, Reinhart AA, Alamneh YA, Pucci MJ, Si Y, Abu-Taleb R, Shearer JP, Demons ST, Tyner SD, Lister T. Zurawski DV, et al. Among authors: lister t. Antimicrob Agents Chemother. 2017 Nov 22;61(12):e01239-17. doi: 10.1128/AAC.01239-17. Print 2017 Dec. Antimicrob Agents Chemother. 2017. PMID: 28947471 Free PMC article.
Assessment of the In Vivo Activity of SPR741 in Combination with Azithromycin against Multidrug-Resistant Enterobacteriaceae Isolates in the Neutropenic Murine Thigh Infection Model.
Stainton SM, Abdelraouf K, Utley L, Pucci MJ, Lister T, Nicolau DP. Stainton SM, et al. Among authors: lister t. Antimicrob Agents Chemother. 2018 Jun 26;62(7):e00239-18. doi: 10.1128/AAC.00239-18. Print 2018 Jul. Antimicrob Agents Chemother. 2018. PMID: 29914941 Free PMC article.
In Vitro Activity Analysis of a New Polymyxin, SPR741, Tested in Combination with Antimicrobial Agents against a Challenge Set of Enterobacteriaceae, Including Molecularly Characterized Strains.
Mendes RE, Rhomberg PR, Lister T, Cotroneo N, Parr TR, Castanheira M. Mendes RE, et al. Among authors: lister t. Antimicrob Agents Chemother. 2020 Dec 16;65(1):e00742-20. doi: 10.1128/AAC.00742-20. Print 2020 Dec 16. Antimicrob Agents Chemother. 2020. PMID: 33077651 Free PMC article.
Safety, Tolerability, Pharmacokinetics, and Drug Interaction Potential of SPR741, an Intravenous Potentiator, after Single and Multiple Ascending Doses and When Combined with β-Lactam Antibiotics in Healthy Subjects.
Eckburg PB, Lister T, Walpole S, Keutzer T, Utley L, Tomayko J, Kopp E, Farinola N, Coleman S. Eckburg PB, et al. Among authors: lister t. Antimicrob Agents Chemother. 2019 Aug 23;63(9):e00892-19. doi: 10.1128/AAC.00892-19. Print 2019 Sep. Antimicrob Agents Chemother. 2019. PMID: 31262767 Free PMC article. Clinical Trial.
471 results