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High-Throughput In Vitro, Ex Vivo, and In Vivo Screen of Adeno-Associated Virus Vectors Based on Physical and Functional Transduction.
Westhaus A, Cabanes-Creus M, Rybicki A, Baltazar G, Navarro RG, Zhu E, Drouyer M, Knight M, Albu RF, Ng BH, Kalajdzic P, Kwiatek M, Hsu K, Santilli G, Gold W, Kramer B, Gonzalez-Cordero A, Thrasher AJ, Alexander IE, Lisowski L. Westhaus A, et al. Among authors: lisowski l. Hum Gene Ther. 2020 May;31(9-10):575-589. doi: 10.1089/hum.2019.264. Epub 2020 Feb 26. Hum Gene Ther. 2020. PMID: 32000541 Free PMC article.
Gene Editing and Rett Syndrome: Does It Make the Cut?
Coorey B, Haase F, Ellaway C, Clarke A, Lisowski L, Gold WA. Coorey B, et al. Among authors: lisowski l. CRISPR J. 2022 Aug;5(4):490-499. doi: 10.1089/crispr.2022.0020. Epub 2022 Jul 26. CRISPR J. 2022. PMID: 35881862 Review.
Single amino acid insertion allows functional transduction of murine hepatocytes with human liver tropic AAV capsids.
Cabanes-Creus M, Navarro RG, Liao SHY, Baltazar G, Drouyer M, Zhu E, Scott S, Luong C, Wilson LOW, Alexander IE, Lisowski L. Cabanes-Creus M, et al. Among authors: lisowski l. Mol Ther Methods Clin Dev. 2021 Apr 24;21:607-620. doi: 10.1016/j.omtm.2021.04.010. eCollection 2021 Jun 11. Mol Ther Methods Clin Dev. 2021. PMID: 34095344 Free PMC article.
Novel human liver-tropic AAV variants define transferable domains that markedly enhance the human tropism of AAV7 and AAV8.
Cabanes-Creus M, Navarro RG, Zhu E, Baltazar G, Liao SHY, Drouyer M, Amaya AK, Scott S, Nguyen LH, Westhaus A, Hebben M, Wilson LOW, Thrasher AJ, Alexander IE, Lisowski L. Cabanes-Creus M, et al. Among authors: lisowski l. Mol Ther Methods Clin Dev. 2021 Nov 25;24:88-101. doi: 10.1016/j.omtm.2021.11.011. eCollection 2022 Mar 10. Mol Ther Methods Clin Dev. 2021. PMID: 34977275 Free PMC article.
Adeno-associated virus serotypes for gene therapeutics.
Lisowski L, Tay SS, Alexander IE. Lisowski L, et al. Curr Opin Pharmacol. 2015 Oct;24:59-67. doi: 10.1016/j.coph.2015.07.006. Epub 2015 Aug 25. Curr Opin Pharmacol. 2015. PMID: 26291407 Review.
Identification of liver-specific enhancer-promoter activity in the 3' untranslated region of the wild-type AAV2 genome.
Logan GJ, Dane AP, Hallwirth CV, Smyth CM, Wilkie EE, Amaya AK, Zhu E, Khandekar N, Ginn SL, Liao SHY, Cunningham SC, Sasaki N, Cabanes-Creus M, Tam PPL, Russell DW, Lisowski L, Alexander IE. Logan GJ, et al. Among authors: lisowski l. Nat Genet. 2017 Aug;49(8):1267-1273. doi: 10.1038/ng.3893. Epub 2017 Jun 19. Nat Genet. 2017. PMID: 28628105
Bioengineered AAV Capsids with Combined High Human Liver Transduction In Vivo and Unique Humoral Seroreactivity.
Paulk NK, Pekrun K, Zhu E, Nygaard S, Li B, Xu J, Chu K, Leborgne C, Dane AP, Haft A, Zhang Y, Zhang F, Morton C, Valentine MB, Davidoff AM, Nathwani AC, Mingozzi F, Grompe M, Alexander IE, Lisowski L, Kay MA. Paulk NK, et al. Among authors: lisowski l. Mol Ther. 2018 Jan 3;26(1):289-303. doi: 10.1016/j.ymthe.2017.09.021. Epub 2017 Sep 25. Mol Ther. 2018. PMID: 29055620 Free PMC article.
108 results