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Counteracting the effects of TNF receptor-1 has therapeutic potential in Alzheimer's disease.
Steeland S, Gorlé N, Vandendriessche C, Balusu S, Brkic M, Van Cauwenberghe C, Van Imschoot G, Van Wonterghem E, De Rycke R, Kremer A, Lippens S, Stopa E, Johanson CE, Libert C, Vandenbroucke RE. Steeland S, et al. Among authors: lippens s. EMBO Mol Med. 2018 Apr;10(4):e8300. doi: 10.15252/emmm.201708300. EMBO Mol Med. 2018. PMID: 29472246 Free PMC article.
Caspase-14 protects against epidermal UVB photodamage and water loss.
Denecker G, Hoste E, Gilbert B, Hochepied T, Ovaere P, Lippens S, Van den Broecke C, Van Damme P, D'Herde K, Hachem JP, Borgonie G, Presland RB, Schoonjans L, Libert C, Vandekerckhove J, Gevaert K, Vandenabeele P, Declercq W. Denecker G, et al. Among authors: lippens s. Nat Cell Biol. 2007 Jun;9(6):666-74. doi: 10.1038/ncb1597. Epub 2007 May 21. Nat Cell Biol. 2007. PMID: 17515931
A novel RIPK4-IRF6 connection is required to prevent epithelial fusions characteristic for popliteal pterygium syndromes.
De Groote P, Tran HT, Fransen M, Tanghe G, Urwyler C, De Craene B, Leurs K, Gilbert B, Van Imschoot G, De Rycke R, Guérin CJ, Holland P, Berx G, Vandenabeele P, Lippens S, Vleminckx K, Declercq W. De Groote P, et al. Among authors: lippens s. Cell Death Differ. 2015 Jun;22(6):1012-24. doi: 10.1038/cdd.2014.191. Epub 2014 Nov 28. Cell Death Differ. 2015. PMID: 25430793 Free PMC article.
Keratinocyte-Specific Ablation of RIPK4 Allows Epidermal Cornification but Impairs Skin Barrier Formation.
Urwyler-Rösselet C, Tanghe G, Leurs K, Gilbert B, De Rycke R, De Bruyne M, Lippens S, Bartunkova S, De Groote P, Niessen C, Haftek M, Vandenabeele P, Declercq W. Urwyler-Rösselet C, et al. Among authors: lippens s. J Invest Dermatol. 2018 Jun;138(6):1268-1278. doi: 10.1016/j.jid.2017.12.031. Epub 2018 Jan 6. J Invest Dermatol. 2018. PMID: 29317263 Free article.
Sensory-Neuropathy-Causing Mutations in ATL3 Cause Aberrant ER Membrane Tethering.
Krols M, Detry S, Asselbergh B, Almeida-Souza L, Kremer A, Lippens S, De Rycke R, De Winter V, Müller FJ, Kurth I, McMahon HT, Savvides SN, Timmerman V, Janssens S. Krols M, et al. Among authors: lippens s. Cell Rep. 2018 May 15;23(7):2026-2038. doi: 10.1016/j.celrep.2018.04.071. Cell Rep. 2018. PMID: 29768202 Free article.
A20 critically controls microglia activation and inhibits inflammasome-dependent neuroinflammation.
Voet S, Mc Guire C, Hagemeyer N, Martens A, Schroeder A, Wieghofer P, Daems C, Staszewski O, Vande Walle L, Jordao MJC, Sze M, Vikkula HK, Demeestere D, Van Imschoot G, Scott CL, Hoste E, Gonçalves A, Guilliams M, Lippens S, Libert C, Vandenbroucke RE, Kim KW, Jung S, Callaerts-Vegh Z, Callaerts P, de Wit J, Lamkanfi M, Prinz M, van Loo G. Voet S, et al. Among authors: lippens s. Nat Commun. 2018 May 23;9(1):2036. doi: 10.1038/s41467-018-04376-5. Nat Commun. 2018. PMID: 29789522 Free PMC article.
Physical and functional interaction between A20 and ATG16L1-WD40 domain in the control of intestinal homeostasis.
Slowicka K, Serramito-Gómez I, Boada-Romero E, Martens A, Sze M, Petta I, Vikkula HK, De Rycke R, Parthoens E, Lippens S, Savvides SN, Wullaert A, Vereecke L, Pimentel-Muiños FX, van Loo G. Slowicka K, et al. Among authors: lippens s. Nat Commun. 2019 Apr 23;10(1):1834. doi: 10.1038/s41467-019-09667-z. Nat Commun. 2019. PMID: 31015422 Free PMC article.
74 results