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Identification and characterization of a temperature sensitive chlorotic soybean mutant.
Hancock CN, Germany T, Redd P, Timmons J, Lipford J, Burns S, Cervantes-Perez SA, Libault M, Shen W, An YC, Kanizay L, Yerka M, Parrott WA. Hancock CN, et al. Among authors: lipford j. bioRxiv [Preprint]. 2024 Feb 3:2024.02.02.578604. doi: 10.1101/2024.02.02.578604. bioRxiv. 2024. PMID: 38352530 Free PMC article. Preprint.
Quantitative measurement of the requirement of diverse protein degradation pathways in MHC class I peptide presentation.
Mamrosh JL, Sherman DJ, Cohen JR, Johnston JA, Joubert MK, Li J, Lipford JR, Lomenick B, Moradian A, Prabhu S, Sweredoski MJ, Vander Lugt B, Verma R, Deshaies RJ. Mamrosh JL, et al. Among authors: lipford jr. Sci Adv. 2023 Jun 23;9(25):eade7890. doi: 10.1126/sciadv.ade7890. Epub 2023 Jun 23. Sci Adv. 2023. PMID: 37352349 Free PMC article.
Diverse alterations associated with resistance to KRAS(G12C) inhibition.
Zhao Y, Murciano-Goroff YR, Xue JY, Ang A, Lucas J, Mai TT, Da Cruz Paula AF, Saiki AY, Mohn D, Achanta P, Sisk AE, Arora KS, Roy RS, Kim D, Li C, Lim LP, Li M, Bahr A, Loomis BR, de Stanchina E, Reis-Filho JS, Weigelt B, Berger M, Riely G, Arbour KC, Lipford JR, Li BT, Lito P. Zhao Y, et al. Among authors: lipford jr. Nature. 2021 Nov;599(7886):679-683. doi: 10.1038/s41586-021-04065-2. Epub 2021 Nov 10. Nature. 2021. PMID: 34759319 Free PMC article.
Mercapturate pathway metabolites of sotorasib, a covalent inhibitor of KRASG12C, are associated with renal toxicity in the Sprague Dawley rat.
Werner JA, Davies R, Wahlstrom J, Dahal UP, Jiang M, Stauber J, David B, Siska W, Thomas B, Ishida K, Humphreys WG, Lipford JR, Monticello TM. Werner JA, et al. Among authors: lipford jr. Toxicol Appl Pharmacol. 2021 Jul 15;423:115578. doi: 10.1016/j.taap.2021.115578. Epub 2021 May 15. Toxicol Appl Pharmacol. 2021. PMID: 34004237
KRASG12C Inhibition with Sotorasib in Advanced Solid Tumors.
Hong DS, Fakih MG, Strickler JH, Desai J, Durm GA, Shapiro GI, Falchook GS, Price TJ, Sacher A, Denlinger CS, Bang YJ, Dy GK, Krauss JC, Kuboki Y, Kuo JC, Coveler AL, Park K, Kim TW, Barlesi F, Munster PN, Ramalingam SS, Burns TF, Meric-Bernstam F, Henary H, Ngang J, Ngarmchamnanrith G, Kim J, Houk BE, Canon J, Lipford JR, Friberg G, Lito P, Govindan R, Li BT. Hong DS, et al. Among authors: lipford jr. N Engl J Med. 2020 Sep 24;383(13):1207-1217. doi: 10.1056/NEJMoa1917239. Epub 2020 Sep 20. N Engl J Med. 2020. PMID: 32955176 Free PMC article. Clinical Trial.
Prospecting for molecular glues.
den Besten W, Lipford JR. den Besten W, et al. Among authors: lipford jr. Nat Chem Biol. 2020 Nov;16(11):1157-1158. doi: 10.1038/s41589-020-0620-z. Nat Chem Biol. 2020. PMID: 32747810 No abstract available.
41 results