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A novel pyrazolo[1,5-a]pyrimidine is a potent inhibitor of cyclin-dependent protein kinases 1, 2, and 9, which demonstrates antitumor effects in human tumor xenografts following oral administration.
Heathcote DA, Patel H, Kroll SH, Hazel P, Periyasamy M, Alikian M, Kanneganti SK, Jogalekar AS, Scheiper B, Barbazanges M, Blum A, Brackow J, Siwicka A, Pace RD, Fuchter MJ, Snyder JP, Liotta DC, Freemont PS, Aboagye EO, Coombes RC, Barrett AG, Ali S. Heathcote DA, et al. Among authors: liotta dc. J Med Chem. 2010 Dec 23;53(24):8508-22. doi: 10.1021/jm100732t. Epub 2010 Nov 16. J Med Chem. 2010. PMID: 21080703
The oxetane ring in taxol.
Wang M, Cornett B, Nettles J, Liotta DC, Snyder JP. Wang M, et al. Among authors: liotta dc. J Org Chem. 2000 Feb 25;65(4):1059-68. doi: 10.1021/jo9916075. J Org Chem. 2000. PMID: 10814054
Nonpeptide inhibitors of measles virus entry.
Sun A, Prussia A, Zhan W, Murray EE, Doyle J, Cheng LT, Yoon JJ, Radchenko EV, Palyulin VA, Compans RW, Liotta DC, Plemper RK, Snyder JP. Sun A, et al. Among authors: liotta dc. J Med Chem. 2006 Aug 24;49(17):5080-92. doi: 10.1021/jm0602559. J Med Chem. 2006. PMID: 16913698
Highly active anticancer curcumin analogues.
Mosley CA, Liotta DC, Snyder JP. Mosley CA, et al. Among authors: liotta dc. Adv Exp Med Biol. 2007;595:77-103. doi: 10.1007/978-0-387-46401-5_2. Adv Exp Med Biol. 2007. PMID: 17569206 Review.
289 results