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The glucocorticoid-induced leucine zipper mediates statin-induced muscle damage.
Hoppstädter J, Valbuena Perez JV, Linnenberger R, Dahlem C, Legroux TM, Hecksteden A, Tse WKF, Flamini S, Andreas A, Herrmann J, Herr C, Müller R, Meyer T, Bals R, Riccardi C, Bruscoli S, Kiemer AK. Hoppstädter J, et al. Among authors: linnenberger r. FASEB J. 2020 Mar;34(3):4684-4701. doi: 10.1096/fj.201902557RRR. Epub 2020 Feb 6. FASEB J. 2020. PMID: 32030813
Amplified Host Defense by Toll-Like Receptor-Mediated Downregulation of the Glucocorticoid-Induced Leucine Zipper (GILZ) in Macrophages.
Hoppstädter J, Diesel B, Linnenberger R, Hachenthal N, Flamini S, Minet M, Leidinger P, Backes C, Grässer F, Meese E, Bruscoli S, Riccardi C, Huwer H, Kiemer AK. Hoppstädter J, et al. Among authors: linnenberger r. Front Immunol. 2019 Jan 22;9:3111. doi: 10.3389/fimmu.2018.03111. eCollection 2018. Front Immunol. 2019. PMID: 30723476 Free PMC article.
Altered glucocorticoid metabolism represents a feature of macroph-aging.
Valbuena Perez JV, Linnenberger R, Dembek A, Bruscoli S, Riccardi C, Schulz MH, Meyer MR, Kiemer AK, Hoppstädter J. Valbuena Perez JV, et al. Among authors: linnenberger r. Aging Cell. 2020 Jun;19(6):e13156. doi: 10.1111/acel.13156. Epub 2020 May 28. Aging Cell. 2020. PMID: 32463582 Free PMC article.