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Low and variable tumor reactivity of the intratumoral TCR repertoire in human cancers.
Scheper W, Kelderman S, Fanchi LF, Linnemann C, Bendle G, de Rooij MAJ, Hirt C, Mezzadra R, Slagter M, Dijkstra K, Kluin RJC, Snaebjornsson P, Milne K, Nelson BH, Zijlmans H, Kenter G, Voest EE, Haanen JBAG, Schumacher TN. Scheper W, et al. Among authors: linnemann c. Nat Med. 2019 Jan;25(1):89-94. doi: 10.1038/s41591-018-0266-5. Epub 2018 Dec 3. Nat Med. 2019. PMID: 30510250
Conditional MHC class I ligands and peptide exchange technology for the human MHC gene products HLA-A1, -A3, -A11, and -B7.
Bakker AH, Hoppes R, Linnemann C, Toebes M, Rodenko B, Berkers CR, Hadrup SR, van Esch WJ, Heemskerk MH, Ovaa H, Schumacher TN. Bakker AH, et al. Among authors: linnemann c. Proc Natl Acad Sci U S A. 2008 Mar 11;105(10):3825-30. doi: 10.1073/pnas.0709717105. Epub 2008 Feb 28. Proc Natl Acad Sci U S A. 2008. PMID: 18308940 Free PMC article.
Lethal graft-versus-host disease in mouse models of T cell receptor gene therapy.
Bendle GM, Linnemann C, Hooijkaas AI, Bies L, de Witte MA, Jorritsma A, Kaiser AD, Pouw N, Debets R, Kieback E, Uckert W, Song JY, Haanen JB, Schumacher TN. Bendle GM, et al. Among authors: linnemann c. Nat Med. 2010 May;16(5):565-70, 1p following 570. doi: 10.1038/nm.2128. Epub 2010 Apr 18. Nat Med. 2010. PMID: 20400962
TIL therapy broadens the tumor-reactive CD8(+) T cell compartment in melanoma patients.
Kvistborg P, Shu CJ, Heemskerk B, Fankhauser M, Thrue CA, Toebes M, van Rooij N, Linnemann C, van Buuren MM, Urbanus JH, Beltman JB, Thor Straten P, Li YF, Robbins PF, Besser MJ, Schachter J, Kenter GG, Dudley ME, Rosenberg SA, Haanen JB, Hadrup SR, Schumacher TN. Kvistborg P, et al. Among authors: linnemann c. Oncoimmunology. 2012 Jul 1;1(4):409-418. doi: 10.4161/onci.18851. Oncoimmunology. 2012. PMID: 22754759 Free PMC article.
High-throughput identification of antigen-specific TCRs by TCR gene capture.
Linnemann C, Heemskerk B, Kvistborg P, Kluin RJ, Bolotin DA, Chen X, Bresser K, Nieuwland M, Schotte R, Michels S, Gomez-Eerland R, Jahn L, Hombrink P, Legrand N, Shu CJ, Mamedov IZ, Velds A, Blank CU, Haanen JB, Turchaninova MA, Kerkhoven RM, Spits H, Hadrup SR, Heemskerk MH, Blankenstein T, Chudakov DM, Bendle GM, Schumacher TN. Linnemann C, et al. Nat Med. 2013 Nov;19(11):1534-41. doi: 10.1038/nm.3359. Epub 2013 Oct 13. Nat Med. 2013. PMID: 24121928
TCR repertoires of intratumoral T-cell subsets.
Linnemann C, Mezzadra R, Schumacher TN. Linnemann C, et al. Immunol Rev. 2014 Jan;257(1):72-82. doi: 10.1111/imr.12140. Immunol Rev. 2014. PMID: 24329790 Review.
Towards error-free profiling of immune repertoires.
Shugay M, Britanova OV, Merzlyak EM, Turchaninova MA, Mamedov IZ, Tuganbaev TR, Bolotin DA, Staroverov DB, Putintseva EV, Plevova K, Linnemann C, Shagin D, Pospisilova S, Lukyanov S, Schumacher TN, Chudakov DM. Shugay M, et al. Among authors: linnemann c. Nat Methods. 2014 Jun;11(6):653-5. doi: 10.1038/nmeth.2960. Epub 2014 May 4. Nat Methods. 2014. PMID: 24793455
159 results