Ling J - Search Results

1

Rodent models of TDP-43: recent advances.

Tsao W, Jeong YH, Lin S, Ling J, Price DL, Chiang PM, Wong PC. Tsao W, et al. Among authors: ling j. Brain Res. 2012 Jun 26;1462:26-39. doi: 10.1016/j.brainres.2012.04.031. Epub 2012 May 1. Brain Res. 2012. PMID: 22608070 Free PMC article. Review.

2

Deletion of TDP-43 down-regulates Tbc1d1, a gene linked to obesity, and alters body fat metabolism.

Chiang PM, Ling J, Jeong YH, Price DL, Aja SM, Wong PC. Chiang PM, et al. Among authors: ling j. Proc Natl Acad Sci U S A. 2010 Sep 14;107(37):16320-4. doi: 10.1073/pnas.1002176107. Epub 2010 Jul 26. Proc Natl Acad Sci U S A. 2010. PMID: 20660762 Free PMC article.

3

TDP-43 repression of nonconserved cryptic exons is compromised in ALS-FTD.

Ling JP, Pletnikova O, Troncoso JC, Wong PC. Ling JP, et al. Science. 2015 Aug 7;349(6248):650-5. doi: 10.1126/science.aab0983. Science. 2015. PMID: 26250685 Free PMC article.

4

PTBP1 and PTBP2 Repress Nonconserved Cryptic Exons.

Ling JP, Chhabra R, Merran JD, Schaughency PM, Wheelan SJ, Corden JL, Wong PC. Ling JP, et al. Cell Rep. 2016 Sep 27;17(1):104-113. doi: 10.1016/j.celrep.2016.08.071. Cell Rep. 2016. PMID: 27681424 Free PMC article.

5

Depletion of TDP-43 decreases fibril and plaque β-amyloid and exacerbates neurodegeneration in an Alzheimer's mouse model.

LaClair KD, Donde A, Ling JP, Jeong YH, Chhabra R, Martin LJ, Wong PC. LaClair KD, et al. Among authors: ling jp. Acta Neuropathol. 2016 Dec;132(6):859-873. doi: 10.1007/s00401-016-1637-y. Epub 2016 Oct 26. Acta Neuropathol. 2016. PMID: 27785573 Free PMC article.

6

An LHX1-Regulated Transcriptional Network Controls Sleep/Wake Coupling and Thermal Resistance of the Central Circadian Clockworks.

Bedont JL, LeGates TA, Buhr E, Bathini A, Ling JP, Bell B, Wu MN, Wong PC, Van Gelder RN, Mongrain V, Hattar S, Blackshaw S. Bedont JL, et al. Curr Biol. 2017 Jan 9;27(1):128-136. doi: 10.1016/j.cub.2016.11.008. Epub 2016 Dec 22. Curr Biol. 2017. PMID: 28017605 Free PMC article.

7

Tdp-43 cryptic exons are highly variable between cell types.

Jeong YH, Ling JP, Lin SZ, Donde AN, Braunstein KE, Majounie E, Traynor BJ, LaClair KD, Lloyd TE, Wong PC. Jeong YH, et al. Among authors: ling jp. Mol Neurodegener. 2017 Feb 2;12(1):13. doi: 10.1186/s13024-016-0144-x. Mol Neurodegener. 2017. PMID: 28153034 Free PMC article.

8

Cryptic exon incorporation occurs in Alzheimer's brain lacking TDP-43 inclusion but exhibiting nuclear clearance of TDP-43.

Sun M, Bell W, LaClair KD, Ling JP, Han H, Kageyama Y, Pletnikova O, Troncoso JC, Wong PC, Chen LL. Sun M, et al. Acta Neuropathol. 2017 Jun;133(6):923-931. doi: 10.1007/s00401-017-1701-2. Epub 2017 Mar 22. Acta Neuropathol. 2017. PMID: 28332094 Free PMC article.

9

Upregulation of ATG7 attenuates motor neuron dysfunction associated with depletion of TARDBP/TDP-43.

Donde A, Sun M, Jeong YH, Wen X, Ling J, Lin S, Braunstein K, Nie S, Wang S, Chen L, Wong PC. Donde A, et al. Among authors: ling j. Autophagy. 2020 Apr;16(4):672-682. doi: 10.1080/15548627.2019.1635379. Epub 2019 Jul 7. Autophagy. 2020. PMID: 31242080 Free PMC article.

10

Splicing repression is a major function of TDP-43 in motor neurons.

Donde A, Sun M, Ling JP, Braunstein KE, Pang B, Wen X, Cheng X, Chen L, Wong PC. Donde A, et al. Acta Neuropathol. 2019 Nov;138(5):813-826. doi: 10.1007/s00401-019-02042-8. Epub 2019 Jul 22. Acta Neuropathol. 2019. PMID: 31332509 Free PMC article.

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