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A chemoproteomic portrait of the oncometabolite fumarate.
Kulkarni RA, Bak DW, Wei D, Bergholtz SE, Briney CA, Shrimp JH, Alpsoy A, Thorpe AL, Bavari AE, Crooks DR, Levy M, Florens L, Washburn MP, Frizzell N, Dykhuizen EC, Weerapana E, Linehan WM, Meier JL. Kulkarni RA, et al. Among authors: linehan wm. Nat Chem Biol. 2019 Apr;15(4):391-400. doi: 10.1038/s41589-018-0217-y. Epub 2019 Feb 4. Nat Chem Biol. 2019. PMID: 30718813 Free PMC article.
HIF and fumarate hydratase in renal cancer.
Sudarshan S, Linehan WM, Neckers L. Sudarshan S, et al. Among authors: linehan wm. Br J Cancer. 2007 Feb 12;96(3):403-7. doi: 10.1038/sj.bjc.6603547. Epub 2007 Jan 9. Br J Cancer. 2007. PMID: 17211469 Free PMC article. Review.
Targeting ABL1-mediated oxidative stress adaptation in fumarate hydratase-deficient cancer.
Sourbier C, Ricketts CJ, Matsumoto S, Crooks DR, Liao PJ, Mannes PZ, Yang Y, Wei MH, Srivastava G, Ghosh S, Chen V, Vocke CD, Merino M, Srinivasan R, Krishna MC, Mitchell JB, Pendergast AM, Rouault TA, Neckers L, Linehan WM. Sourbier C, et al. Among authors: linehan wm. Cancer Cell. 2014 Dec 8;26(6):840-850. doi: 10.1016/j.ccell.2014.10.005. Cancer Cell. 2014. PMID: 25490448 Free PMC article.
SnapShot: Renal Cell Carcinoma.
Ricketts CJ, Crooks DR, Sourbier C, Schmidt LS, Srinivasan R, Linehan WM. Ricketts CJ, et al. Among authors: linehan wm. Cancer Cell. 2016 Apr 11;29(4):610-610.e1. doi: 10.1016/j.ccell.2016.03.021. Cancer Cell. 2016. PMID: 27070709 Free article.
Targeting HIF2α in Clear-Cell Renal Cell Carcinoma.
Ricketts CJ, Crooks DR, Linehan WM. Ricketts CJ, et al. Among authors: linehan wm. Cancer Cell. 2016 Oct 10;30(4):515-517. doi: 10.1016/j.ccell.2016.09.016. Cancer Cell. 2016. PMID: 27728802 Free article.
Co-opting a Bioorthogonal Reaction for Oncometabolite Detection.
Zengeya TT, Garlick JM, Kulkarni RA, Miley M, Roberts AM, Yang Y, Crooks DR, Sourbier C, Linehan WM, Meier JL. Zengeya TT, et al. Among authors: linehan wm. J Am Chem Soc. 2016 Dec 14;138(49):15813-15816. doi: 10.1021/jacs.6b09706. Epub 2016 Nov 30. J Am Chem Soc. 2016. PMID: 27960310 Free PMC article.
Discovering Targets of Non-enzymatic Acylation by Thioester Reactivity Profiling.
Kulkarni RA, Worth AJ, Zengeya TT, Shrimp JH, Garlick JM, Roberts AM, Montgomery DC, Sourbier C, Gibbs BK, Mesaros C, Tsai YC, Das S, Chan KC, Zhou M, Andresson T, Weissman AM, Linehan WM, Blair IA, Snyder NW, Meier JL. Kulkarni RA, et al. Among authors: linehan wm. Cell Chem Biol. 2017 Feb 16;24(2):231-242. doi: 10.1016/j.chembiol.2017.01.002. Epub 2017 Feb 2. Cell Chem Biol. 2017. PMID: 28163016 Free PMC article.
798 results