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CD8+ T cells specific for an immunodominant SARS-CoV-2 nucleocapsid epitope cross-react with selective seasonal coronaviruses.
Lineburg KE, Grant EJ, Swaminathan S, Chatzileontiadou DSM, Szeto C, Sloane H, Panikkar A, Raju J, Crooks P, Rehan S, Nguyen AT, Lekieffre L, Neller MA, Tong ZWM, Jayasinghe D, Chew KY, Lobos CA, Halim H, Burrows JM, Riboldi-Tunnicliffe A, Chen W, D'Orsogna L, Khanna R, Short KR, Smith C, Gras S. Lineburg KE, et al. Immunity. 2021 May 11;54(5):1055-1065.e5. doi: 10.1016/j.immuni.2021.04.006. Epub 2021 Apr 13. Immunity. 2021. PMID: 33945786 Free PMC article.
Induced regulatory T cells promote tolerance when stabilized by rapamycin and IL-2 in vivo.
Zhang P, Tey SK, Koyama M, Kuns RD, Olver SD, Lineburg KE, Lor M, Teal BE, Raffelt NC, Raju J, Leveque L, Markey KA, Varelias A, Clouston AD, Lane SW, MacDonald KP, Hill GR. Zhang P, et al. Among authors: lineburg ke. J Immunol. 2013 Nov 15;191(10):5291-303. doi: 10.4049/jimmunol.1301181. Epub 2013 Oct 11. J Immunol. 2013. PMID: 24123683
Autologous CMV-specific T cells are a safe adjuvant immunotherapy for primary glioblastoma multiforme.
Smith C, Lineburg KE, Martins JP, Ambalathingal GR, Neller MA, Morrison B, Matthews KK, Rehan S, Crooks P, Panikkar A, Beagley L, Le Texier L, Srihari S, Walker D, Khanna R. Smith C, et al. Among authors: lineburg ke. J Clin Invest. 2020 Nov 2;130(11):6041-6053. doi: 10.1172/JCI138649. J Clin Invest. 2020. PMID: 32750039 Free PMC article. Clinical Trial.
Rapid whole-blood assay to detect SARS-CoV-2-specific memory T-cell immunity following a single dose of AstraZeneca ChAdOx1-S COVID-19 vaccine.
Lineburg KE, Neller MA, Ambalathingal GR, Le Texier L, Raju J, Swaminathan S, Lekieffre L, Smith C, Rehan S, Crooks P, Panikkar A, Srihari S, Khanna R, Smith C. Lineburg KE, et al. Clin Transl Immunology. 2021 Aug 12;10(8):e1326. doi: 10.1002/cti2.1326. eCollection 2021. Clin Transl Immunology. 2021. PMID: 34408875 Free PMC article.
SARS-CoV-2-specific T cells generated for adoptive immunotherapy are capable of recognizing multiple SARS-CoV-2 variants.
Panikkar A, Lineburg KE, Raju J, Chew KY, Ambalathingal GR, Rehan S, Swaminathan S, Crooks P, Le Texier L, Beagley L, Best S, Solomon M, Matthews KK, Srihari S, Neller MA, Short KR, Khanna R, Smith C. Panikkar A, et al. Among authors: lineburg ke. PLoS Pathog. 2022 Feb 14;18(2):e1010339. doi: 10.1371/journal.ppat.1010339. eCollection 2022 Feb. PLoS Pathog. 2022. PMID: 35157735 Free PMC article.
Limited Recognition of Highly Conserved Regions of SARS-CoV-2.
Swaminathan S, Lineburg KE, Ambalathingal GR, Crooks P, Grant EJ, Mohan SV, Raju J, Panikkar A, Le Texier L, Tong ZWM, Chew KY, Neller MA, Short KR, Gowda H, Gras S, Khanna R, Smith C. Swaminathan S, et al. Among authors: lineburg ke. Microbiol Spectr. 2022 Feb 23;10(1):e0278021. doi: 10.1128/spectrum.02780-21. Epub 2022 Feb 23. Microbiol Spectr. 2022. PMID: 35196796 Free PMC article.
Ablation of CD8+ T cell recognition of an immunodominant epitope in SARS-CoV-2 Omicron variants BA.1, BA.2 and BA.3.
Swaminathan S, Lineburg KE, Panikkar A, Raju J, Murdolo LD, Szeto C, Crooks P, Le Texier L, Rehan S, Dewar-Oldis MJ, Barnard PJ, Ambalathingal GR, Neller MA, Short KR, Gras S, Khanna R, Smith C. Swaminathan S, et al. Among authors: lineburg ke. Nat Commun. 2022 Oct 27;13(1):6387. doi: 10.1038/s41467-022-34180-1. Nat Commun. 2022. PMID: 36302758 Free PMC article.
In vivo inhibition of nuclear ACE2 translocation protects against SARS-CoV-2 replication and lung damage through epigenetic imprinting.
Tu WJ, Melino M, Dunn J, McCuaig RD, Bielefeldt-Ohmann H, Tsimbalyuk S, Forwood JK, Ahuja T, Vandermeide J, Tan X, Tran M, Nguyen Q, Zhang L, Nam A, Pan L, Liang Y, Smith C, Lineburg K, Nguyen TH, Sng JDJ, Tong ZWM, Chew KY, Short KR, Le Grand R, Seddiki N, Rao S. Tu WJ, et al. Nat Commun. 2023 Jun 27;14(1):3680. doi: 10.1038/s41467-023-39341-4. Nat Commun. 2023. PMID: 37369668 Free PMC article.
45 results