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The multifunctional protein E4F1 links P53 to lipid metabolism in adipocytes.
Lacroix M, Linares LK, Rueda-Rincon N, Bloch K, Di Michele M, De Blasio C, Fau C, Gayte L, Blanchet E, Mairal A, Derua R, Cardona F, Beuzelin D, Annicotte JS, Pirot N, Torro A, Tinahones FJ, Bernex F, Bertrand-Michel J, Langin D, Fajas L, Swinnen JV, Le Cam L. Lacroix M, et al. Among authors: linares lk. Nat Commun. 2021 Dec 2;12(1):7037. doi: 10.1038/s41467-021-27307-3. Nat Commun. 2021. PMID: 34857760 Free PMC article.
Chromatin-bound MDM2, a new player in metabolism.
Riscal R, Le Cam L, Linares LK. Riscal R, et al. Among authors: linares lk. Mol Cell Oncol. 2016 Jul 15;3(5):e1210560. doi: 10.1080/23723556.2016.1210560. eCollection 2016. Mol Cell Oncol. 2016. PMID: 27857973 Free PMC article.
The p53 Pathway and Metabolism: The Tree That Hides the Forest.
Lahalle A, Lacroix M, De Blasio C, Cissé MY, Linares LK, Le Cam L. Lahalle A, et al. Among authors: linares lk. Cancers (Basel). 2021 Jan 4;13(1):133. doi: 10.3390/cancers13010133. Cancers (Basel). 2021. PMID: 33406607 Free PMC article. Review.
Transcription factor E4F1 is essential for epidermal stem cell maintenance and skin homeostasis.
Lacroix M, Caramel J, Goguet-Rubio P, Linares LK, Estrach S, Hatchi E, Rodier G, Lledo G, de Bettignies C, Thépot A, Deraison C, Chébli K, Hovnanian A, Hainaut P, Dubus P, Sardet C, Le Cam L. Lacroix M, et al. Among authors: linares lk. Proc Natl Acad Sci U S A. 2010 Dec 7;107(49):21076-81. doi: 10.1073/pnas.1010167107. Epub 2010 Nov 18. Proc Natl Acad Sci U S A. 2010. PMID: 21088222 Free PMC article.
Targeting MDM2-dependent serine metabolism as a therapeutic strategy for liposarcoma.
Cissé MY, Pyrdziak S, Firmin N, Gayte L, Heuillet M, Bellvert F, Fuentes M, Delpech H, Riscal R, Arena G, Chibon F, Le Gellec S, Maran-Gonzalez A, Chateau MC, Theillet C, Carrere S, Portais JC, Le Cam L, Linares LK. Cissé MY, et al. Among authors: linares lk. Sci Transl Med. 2020 Jun 10;12(547):eaay2163. doi: 10.1126/scitranslmed.aay2163. Sci Transl Med. 2020. PMID: 32522803
Chromatin-Bound MDM2 Regulates Serine Metabolism and Redox Homeostasis Independently of p53.
Riscal R, Schrepfer E, Arena G, Cissé MY, Bellvert F, Heuillet M, Rambow F, Bonneil E, Sabourdy F, Vincent C, Ait-Arsa I, Levade T, Thibaut P, Marine JC, Portais JC, Sarry JE, Le Cam L, Linares LK. Riscal R, et al. Among authors: linares lk. Mol Cell. 2016 Jun 16;62(6):890-902. doi: 10.1016/j.molcel.2016.04.033. Epub 2016 Jun 2. Mol Cell. 2016. PMID: 27264869 Free article.
BAT3 modulates p300-dependent acetylation of p53 and autophagy-related protein 7 (ATG7) during autophagy.
Sebti S, Prébois C, Pérez-Gracia E, Bauvy C, Desmots F, Pirot N, Gongora C, Bach AS, Hubberstey AV, Palissot V, Berchem G, Codogno P, Linares LK, Liaudet-Coopman E, Pattingre S. Sebti S, et al. Among authors: linares lk. Proc Natl Acad Sci U S A. 2014 Mar 18;111(11):4115-20. doi: 10.1073/pnas.1313618111. Epub 2014 Mar 3. Proc Natl Acad Sci U S A. 2014. PMID: 24591579 Free PMC article.
37 results