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Hypoxia suppresses myocardial survival pathway through HIF-1α-IGFBP-3-dependent signaling and enhances cardiomyocyte autophagic and apoptotic effects mainly via FoxO3a-induced BNIP3 expression.
Feng CC, Lin CC, Lai YP, Chen TS, Marthandam Asokan S, Lin JY, Lin KH, Viswanadha VP, Kuo WW, Huang CY. Feng CC, et al. Among authors: lin kh, lin cc, lin jy. Growth Factors. 2016 Aug;34(3-4):73-86. doi: 10.1080/08977194.2016.1191480. Epub 2016 Jul 1. Growth Factors. 2016. PMID: 27366871
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