Lin JT - Search Results

1

How GRAIL controls Treg function to maintain self-tolerance.

Fathman CG, Yip L, Gómez-Martín D, Yu M, Seroogy CM, Hurt CR, Lin JT, Jenks JA, Nadeau KC, Soares L. Fathman CG, et al. Among authors: lin jt. Front Immunol. 2022 Dec 8;13:1046631. doi: 10.3389/fimmu.2022.1046631. eCollection 2022. Front Immunol. 2022. PMID: 36569931 Free PMC article.

2

Naive CD4 t cell proliferation is controlled by mammalian target of rapamycin regulation of GRAIL expression.

Lin JT, Lineberry NB, Kattah MG, Su LL, Utz PJ, Fathman CG, Wu L. Lin JT, et al. J Immunol. 2009 May 15;182(10):5919-28. doi: 10.4049/jimmunol.0803986. J Immunol. 2009. PMID: 19414743 Free PMC article.

3

GRAIL is up-regulated in CD4+ CD25+ T regulatory cells and is sufficient for conversion of T cells to a regulatory phenotype.

MacKenzie DA, Schartner J, Lin J, Timmel A, Jennens-Clough M, Fathman CG, Seroogy CM. MacKenzie DA, et al. J Biol Chem. 2007 Mar 30;282(13):9696-9702. doi: 10.1074/jbc.M604192200. Epub 2007 Jan 26. J Biol Chem. 2007. PMID: 17259178 Free article.

4

Cutting edge: The transmembrane E3 ligase GRAIL ubiquitinates the costimulatory molecule CD40 ligand during the induction of T cell anergy.

Lineberry NB, Su LL, Lin JT, Coffey GP, Seroogy CM, Fathman CG. Lineberry NB, et al. Among authors: lin jt. J Immunol. 2008 Aug 1;181(3):1622-6. doi: 10.4049/jimmunol.181.3.1622. J Immunol. 2008. PMID: 18641297 Free PMC article.

5

The transmembrane E3 ligase GRAIL ubiquitinates and degrades CD83 on CD4 T cells.

Su LL, Iwai H, Lin JT, Fathman CG. Su LL, et al. Among authors: lin jt. J Immunol. 2009 Jul 1;183(1):438-44. doi: 10.4049/jimmunol.0900204. J Immunol. 2009. PMID: 19542455 Free PMC article.

6

GRAIL: a unique mediator of CD4 T-lymphocyte unresponsiveness.

Whiting CC, Su LL, Lin JT, Fathman CG. Whiting CC, et al. Among authors: lin jt. FEBS J. 2011 Jan;278(1):47-58. doi: 10.1111/j.1742-4658.2010.07922.x. Epub 2010 Nov 16. FEBS J. 2011. PMID: 21078124 Free PMC article. Review.

7

Differential mTOR and ERK pathway utilization by effector CD4 T cells suggests combinatorial drug therapy of arthritis.

Lin JT, Stein EA, Wong MT, Kalpathy KJ, Su LL, Utz PJ, Robinson WH, Fathman CG. Lin JT, et al. Clin Immunol. 2012 Feb;142(2):127-38. doi: 10.1016/j.clim.2011.09.008. Epub 2011 Oct 1. Clin Immunol. 2012. PMID: 22075384 Free PMC article.

8

Exploiting a natural conformational switch to engineer an interleukin-2 'superkine'.

Levin AM, Bates DL, Ring AM, Krieg C, Lin JT, Su L, Moraga I, Raeber ME, Bowman GR, Novick P, Pande VS, Fathman CG, Boyman O, Garcia KC. Levin AM, et al. Among authors: lin jt. Nature. 2012 Mar 25;484(7395):529-33. doi: 10.1038/nature10975. Nature. 2012. PMID: 22446627 Free PMC article.

9

Therapeutic effect of CD137 immunomodulation in lymphoma and its enhancement by Treg depletion.

Houot R, Goldstein MJ, Kohrt HE, Myklebust JH, Alizadeh AA, Lin JT, Irish JM, Torchia JA, Kolstad A, Chen L, Levy R. Houot R, et al. Among authors: lin jt. Blood. 2009 Oct 15;114(16):3431-8. doi: 10.1182/blood-2009-05-223958. Epub 2009 Jul 29. Blood. 2009. PMID: 19641184 Free PMC article.

10

Adoptive cell therapy for lymphoma with CD4 T cells depleted of CD137-expressing regulatory T cells.

Goldstein MJ, Kohrt HE, Houot R, Varghese B, Lin JT, Swanson E, Levy R. Goldstein MJ, et al. Among authors: lin jt. Cancer Res. 2012 Mar 1;72(5):1239-47. doi: 10.1158/0008-5472.CAN-11-3375. Epub 2012 Jan 9. Cancer Res. 2012. PMID: 22232735 Free PMC article.

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