Lin JC - Search Results

1

The antitumor agent PBT-1 directly targets HSP90 and hnRNP A2/B1 and inhibits lung adenocarcinoma growth and metastasis.

Chen CY, Yang SC, Lee KH, Yang X, Wei LY, Chow LP, Wang TC, Hong TM, Lin JC, Kuan C, Yang PC. Chen CY, et al. Among authors: lin jc. J Med Chem. 2014 Feb 13;57(3):677-85. doi: 10.1021/jm401686b. Epub 2014 Jan 31. J Med Chem. 2014. PMID: 24428777 Free PMC article.

2

Phenanthrene-based tylophorine-1 (PBT-1) inhibits lung cancer cell growth through the Akt and NF-kappaB pathways.

Lin JC, Yang SC, Hong TM, Yu SL, Shi Q, Wei L, Chen HY, Yang PC, Lee KH. Lin JC, et al. J Med Chem. 2009 Apr 9;52(7):1903-11. doi: 10.1021/jm801344j. J Med Chem. 2009. PMID: 19284764 Free PMC article.

3

Antitumor agents 268. Design, synthesis, and mechanistic studies of new 9-substituted phenanthrene-based tylophorine analogues as potent cytotoxic agents.

Yang X, Shi Q, Liu YN, Zhao G, Bastow KF, Lin JC, Yang SC, Yang PC, Lee KH. Yang X, et al. Among authors: lin jc. J Med Chem. 2009 Aug 27;52(16):5262-8. doi: 10.1021/jm9009263. J Med Chem. 2009. PMID: 19645447 Free PMC article.

4

Antitumor agents 288: design, synthesis, SAR, and biological studies of novel heteroatom-incorporated antofine and cryptopleurine analogues as potent and selective antitumor agents.

Yang X, Shi Q, Yang SC, Chen CY, Yu SL, Bastow KF, Morris-Natschke SL, Wu PC, Lai CY, Wu TS, Pan SL, Teng CM, Lin JC, Yang PC, Lee KH. Yang X, et al. Among authors: lin jc. J Med Chem. 2011 Jul 28;54(14):5097-107. doi: 10.1021/jm200330s. Epub 2011 Jun 28. J Med Chem. 2011. PMID: 21668000 Free PMC article.

5

MicroRNA-135b promotes lung cancer metastasis by regulating multiple targets in the Hippo pathway and LZTS1.

Lin CW, Chang YL, Chang YC, Lin JC, Chen CC, Pan SH, Wu CT, Chen HY, Yang SC, Hong TM, Yang PC. Lin CW, et al. Among authors: lin jc. Nat Commun. 2013;4:1877. doi: 10.1038/ncomms2876. Nat Commun. 2013. PMID: 23695671 Free article.

6

Antitumor agents 283. Further elaboration of desmosdumotin C analogs as potent antitumor agents: activation of spindle assembly checkpoint as possible mode of action.

Nakagawa-Goto K, Wu PC, Bastow KF, Yang SC, Yu SL, Chen HY, Lin JC, Goto M, Morris-Natschke SL, Yang PC, Lee KH. Nakagawa-Goto K, et al. Among authors: lin jc. Bioorg Med Chem. 2011 Mar 1;19(5):1816-22. doi: 10.1016/j.bmc.2011.01.001. Epub 2011 Jan 15. Bioorg Med Chem. 2011. PMID: 21296579 Free PMC article.

7

TROP2 is epigenetically inactivated and modulates IGF-1R signalling in lung adenocarcinoma.

Lin JC, Wu YY, Wu JY, Lin TC, Wu CT, Chang YL, Jou YS, Hong TM, Yang PC. Lin JC, et al. Among authors: lin tc. EMBO Mol Med. 2012 Jun;4(6):472-85. doi: 10.1002/emmm.201200222. Epub 2012 Mar 15. EMBO Mol Med. 2012. PMID: 22419550 Free PMC article.

8

Modulation of the expression of the invasion-suppressor CRMP-1 by cyclooxygenase-2 inhibition via reciprocal regulation of Sp1 and C/EBPalpha.

Wu CC, Lin JC, Yang SC, Lin CW, Chen JJ, Shih JY, Hong TM, Yang PC. Wu CC, et al. Among authors: lin cw, lin jc. Mol Cancer Ther. 2008 Jun;7(6):1365-75. doi: 10.1158/1535-7163.MCT-08-0091. Epub 2008 Jun 4. Mol Cancer Ther. 2008. PMID: 18524846

9

FJU-C4, a new 2-pyridone compound, attenuates lipopolysaccharide-induced systemic inflammation via p38MAPK and NF-κB in mice.

Liu JS, Jung F, Yang SH, Chou SS, Huang JL, Lu CL, Huang GL, Yang PC, Lin JC, Jow GM. Liu JS, et al. Among authors: lin jc. PLoS One. 2013 Dec 23;8(12):e82877. doi: 10.1371/journal.pone.0082877. eCollection 2013. PLoS One. 2013. PMID: 24376600 Free PMC article.

10

Modulation of mitogen-activated protein kinase cascades by differentiation-1 protein: acquired drug resistance of hormone independent prostate cancer cells.

Lin JC, Chang SY, Hsieh DS, Lee CF, Yu DS. Lin JC, et al. J Urol. 2005 Nov;174(5):2022-6. doi: 10.1097/01.ju.0000176476.14572.39. J Urol. 2005. PMID: 16217386

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