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A Reactive Antibody Platform for One-Step Production of Antibody-Drug Conjugates through a Diels-Alder Reaction with Maleimide.
St Amant AH, Huang F, Lin J, Lemen D, Chakiath C, Mao S, Fazenbaker C, Zhong H, Harper J, Xu W, Patel N, Adams L, Vijayakrishnan B, Howard PW, Marelli M, Wu H, Gao C, Read de Alaniz J, Christie RJ. St Amant AH, et al. Among authors: lin j. Bioconjug Chem. 2019 Sep 18;30(9):2340-2348. doi: 10.1021/acs.bioconjchem.9b00436. Epub 2019 Aug 19. Bioconjug Chem. 2019. PMID: 31380623
A Biparatopic HER2-Targeting Antibody-Drug Conjugate Induces Tumor Regression in Primary Models Refractory to or Ineligible for HER2-Targeted Therapy.
Li JY, Perry SR, Muniz-Medina V, Wang X, Wetzel LK, Rebelatto MC, Hinrichs MJ, Bezabeh BZ, Fleming RL, Dimasi N, Feng H, Toader D, Yuan AQ, Xu L, Lin J, Gao C, Wu H, Dixit R, Osbourn JK, Coats SR. Li JY, et al. Among authors: lin j. Cancer Cell. 2016 Jan 11;29(1):117-29. doi: 10.1016/j.ccell.2015.12.008. Cancer Cell. 2016. PMID: 26766593 Free article.
A Diene-Containing Noncanonical Amino Acid Enables Dual Functionality in Proteins: Rapid Diels-Alder Reaction with Maleimide or Proximity-Based Dimerization.
St Amant AH, Huang F, Lin J, Rickert K, Oganesyan V, Lemen D, Mao S, Harper J, Marelli M, Wu H, Gao C, Read de Alaniz J, Christie RJ. St Amant AH, et al. Among authors: lin j. Angew Chem Int Ed Engl. 2019 Jun 17;58(25):8489-8493. doi: 10.1002/anie.201903494. Epub 2019 May 14. Angew Chem Int Ed Engl. 2019. PMID: 31018033 Free PMC article.
A Biparatopic HER2-Targeting Antibody-Drug Conjugate Induces Tumor Regression in Primary Models Refractory to or Ineligible for HER2-Targeted Therapy.
Li JY, Perry SR, Muniz-Medina V, Wang X, Wetzel LK, Rebelatto MC, Masson Hinrichs MJ, Bezabeh BZ, Fleming RL, Dimasi N, Feng H, Toader D, Yuan AQ, Xu L, Lin J, Gao C, Wu H, Dixit R, Osbourn JK, Coats SR. Li JY, et al. Among authors: lin j. Cancer Cell. 2019 Jun 10;35(6):948-949. doi: 10.1016/j.ccell.2019.05.010. Cancer Cell. 2019. PMID: 31185215 Free article. No abstract available.
T follicular helper-like cells contribute to skin fibrosis.
Taylor DK, Mittereder N, Kuta E, Delaney T, Burwell T, Dacosta K, Zhao W, Cheng LI, Brown C, Boutrin A, Guo X, White WI, Zhu J, Dong H, Bowen MA, Lin J, Gao C, Yu L, Ramaswamy M, Gaudreau MC, Woods R, Herbst R, Carlesso G. Taylor DK, et al. Among authors: lin j. Sci Transl Med. 2018 Mar 7;10(431):eaaf5307. doi: 10.1126/scitranslmed.aaf5307. Sci Transl Med. 2018. PMID: 29514998
Identification of broadly protective human antibodies to Pseudomonas aeruginosa exopolysaccharide Psl by phenotypic screening.
DiGiandomenico A, Warrener P, Hamilton M, Guillard S, Ravn P, Minter R, Camara MM, Venkatraman V, Macgill RS, Lin J, Wang Q, Keller AE, Bonnell JC, Tomich M, Jermutus L, McCarthy MP, Melnick DA, Suzich JA, Stover CK. DiGiandomenico A, et al. Among authors: lin j. J Exp Med. 2012 Jul 2;209(7):1273-87. doi: 10.1084/jem.20120033. Epub 2012 Jun 25. J Exp Med. 2012. PMID: 22734046 Free PMC article.
Qualification of a Biolayer Interferometry Assay to Support AZD7442 Resistance Monitoring.
Brady T, Zhang T, Tuffy KM, Haskins N, Du Q, Lin J, Kaplan G, Novick S, Roe TL, Ren K, Rosenthal K, McTamney PM, Abram ME, Streicher K, Kelly EJ. Brady T, et al. Among authors: lin j. Microbiol Spectr. 2022 Oct 26;10(5):e0103422. doi: 10.1128/spectrum.01034-22. Epub 2022 Aug 22. Microbiol Spectr. 2022. PMID: 35993765 Free PMC article.
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