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Elevated sphingosine-1-phosphate promotes sickling and sickle cell disease progression.
Zhang Y, Berka V, Song A, Sun K, Wang W, Zhang W, Ning C, Li C, Zhang Q, Bogdanov M, Alexander DC, Milburn MV, Ahmed MH, Lin H, Idowu M, Zhang J, Kato GJ, Abdulmalik OY, Zhang W, Dowhan W, Kellems RE, Zhang P, Jin J, Safo M, Tsai AL, Juneja HS, Xia Y. Zhang Y, et al. Among authors: lin h. J Clin Invest. 2014 Jun;124(6):2750-61. doi: 10.1172/JCI74604. Epub 2014 May 16. J Clin Invest. 2014. PMID: 24837436 Free PMC article.
The NEK1 interactor, C21ORF2, is required for efficient DNA damage repair.
Fang X, Lin H, Wang X, Zuo Q, Qin J, Zhang P. Fang X, et al. Among authors: lin h. Acta Biochim Biophys Sin (Shanghai). 2015 Oct;47(10):834-41. doi: 10.1093/abbs/gmv076. Epub 2015 Aug 18. Acta Biochim Biophys Sin (Shanghai). 2015. PMID: 26290490 Free PMC article.
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