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A novel pentamethoxyflavone down-regulates tumor cell survival and proliferative and angiogenic gene products through inhibition of IκB kinase activation and sensitizes tumor cells to apoptosis by cytokines and chemotherapeutic agents.
Phromnoi K, Reuter S, Sung B, Prasad S, Kannappan R, Yadav VR, Chanmahasathien W, Limtrakul P, Aggarwal BB. Phromnoi K, et al. Among authors: limtrakul p. Mol Pharmacol. 2011 Feb;79(2):279-89. doi: 10.1124/mol.110.067512. Epub 2010 Oct 7. Mol Pharmacol. 2011. PMID: 20930110 Free PMC article. Retracted.
Curcumin, demethoxycurcumin, bisdemethoxycurcumin, tetrahydrocurcumin and turmerones differentially regulate anti-inflammatory and anti-proliferative responses through a ROS-independent mechanism.
Sandur SK, Pandey MK, Sung B, Ahn KS, Murakami A, Sethi G, Limtrakul P, Badmaev V, Aggarwal BB. Sandur SK, et al. Among authors: limtrakul p. Carcinogenesis. 2007 Aug;28(8):1765-73. doi: 10.1093/carcin/bgm123. Epub 2007 May 23. Carcinogenesis. 2007. PMID: 17522064
67 results