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Immunosuppression reduces rAAV2.5T neutralizing antibodies that limit efficacy following repeat dosing to ferret lungs.
Tang Y, Fakhari S, Huntemann ED, Feng Z, Wu P, Feng WY, Lei J, Yuan F, Excoffon KJ, Wang K, Limberis MP, Kolbeck R, Yan Z, Engelhardt JF. Tang Y, et al. Among authors: limberis mp. Mol Ther Methods Clin Dev. 2023 Mar 2;29:70-80. doi: 10.1016/j.omtm.2023.02.015. eCollection 2023 Jun 8. Mol Ther Methods Clin Dev. 2023. PMID: 36950451 Free PMC article.
Durable transgene expression and efficient re-administration after rAAV2.5T-mediated fCFTRΔR gene delivery to adult ferret lungs.
Tang Y, Ebadi M, Lei J, Feng Z, Fakhari S, Wu P, Smith MD, Limberis MP, Kolbeck R, Excoffon KJ, Yan Z, Engelhardt JF. Tang Y, et al. Among authors: limberis mp. Mol Ther Methods Clin Dev. 2024 Mar 28;32(2):101244. doi: 10.1016/j.omtm.2024.101244. eCollection 2024 Jun 13. Mol Ther Methods Clin Dev. 2024. PMID: 38638546 Free PMC article.
Self-reactive CFTR T cells in humans: implications for gene therapy.
Calcedo R, Griesenbach U, Dorgan DJ, Soussi S, Boyd AC, Davies JC, Higgins TE, Hyde SC, Gill DR, Innes JA, Porteous DJ, Alton EW, Wilson JM, Limberis MP. Calcedo R, et al. Among authors: limberis mp. Hum Gene Ther Clin Dev. 2013 Sep;24(3):108-15. doi: 10.1089/humc.2012.249. Epub 2013 Jul 19. Hum Gene Ther Clin Dev. 2013. PMID: 23790242 Free PMC article.
Biodistribution of AAV8 vectors expressing human low-density lipoprotein receptor in a mouse model of homozygous familial hypercholesterolemia.
Chen SJ, Sanmiguel J, Lock M, McMenamin D, Draper C, Limberis MP, Kassim SH, Somanathan S, Bell P, Johnston JC, Rader DJ, Wilson JM. Chen SJ, et al. Among authors: limberis mp. Hum Gene Ther Clin Dev. 2013 Dec;24(4):154-60. doi: 10.1089/humc.2013.082. Epub 2013 Nov 9. Hum Gene Ther Clin Dev. 2013. PMID: 24070336 Free PMC article.
48 results