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Evidence that the human cell cycle is a series of uncoupled, memoryless phases.
Chao HX, Fakhreddin RI, Shimerov HK, Kedziora KM, Kumar RJ, Perez J, Limas JC, Grant GD, Cook JG, Gupta GP, Purvis JE. Chao HX, et al. Among authors: limas jc. Mol Syst Biol. 2019 Mar 18;15(3):e8604. doi: 10.15252/msb.20188604. Mol Syst Biol. 2019. PMID: 30886052 Free PMC article.
The molecular architecture of cell cycle arrest.
Stallaert W, Taylor SR, Kedziora KM, Taylor CD, Sobon HK, Young CL, Limas JC, Varblow Holloway J, Johnson MS, Cook JG, Purvis JE. Stallaert W, et al. Among authors: limas jc. Mol Syst Biol. 2022 Sep;18(9):e11087. doi: 10.15252/msb.202211087. Mol Syst Biol. 2022. PMID: 36161508 Free PMC article.
Quantitative profiling of adaptation to cyclin E overproduction.
Limas JC, Littlejohn AN, House AM, Kedziora KM, Mouery BL, Ma B, Fleifel D, Walens A, Aleman MM, Dominguez D, Cook JG. Limas JC, et al. Life Sci Alliance. 2022 Feb 16;5(5):e202201378. doi: 10.26508/lsa.202201378. Print 2022 May. Life Sci Alliance. 2022. PMID: 35173014 Free PMC article.
SGC-AAK1-1: A Chemical Probe Targeting AAK1 and BMP2K.
Wells C, Couñago RM, Limas JC, Almeida TL, Cook JG, Drewry DH, Elkins JM, Gileadi O, Kapadia NR, Lorente-Macias A, Pickett JE, Riemen A, Ruela-de-Sousa RR, Willson TM, Zhang C, Zuercher WJ, Zutshi R, Axtman AD. Wells C, et al. Among authors: limas jc. ACS Med Chem Lett. 2019 Oct 23;11(3):340-345. doi: 10.1021/acsmedchemlett.9b00399. eCollection 2020 Mar 12. ACS Med Chem Lett. 2019. PMID: 32184967 Free PMC article.
Combination therapy with potent PI3K and MAPK inhibitors overcomes adaptive kinome resistance to single agents in preclinical models of glioblastoma.
McNeill RS, Canoutas DA, Stuhlmiller TJ, Dhruv HD, Irvin DM, Bash RE, Angus SP, Herring LE, Simon JM, Skinner KR, Limas JC, Chen X, Schmid RS, Siegel MB, Van Swearingen AED, Hadler MJ, Sulman EP, Sarkaria JN, Anders CK, Graves LM, Berens ME, Johnson GL, Miller CR. McNeill RS, et al. Among authors: limas jc. Neuro Oncol. 2017 Oct 19;19(11):1469-1480. doi: 10.1093/neuonc/nox044. Neuro Oncol. 2017. PMID: 28379424 Free PMC article.