Lim SP - Search Results

1

Ten years of dengue drug discovery: progress and prospects.

Lim SP, Wang QY, Noble CG, Chen YL, Dong H, Zou B, Yokokawa F, Nilar S, Smith P, Beer D, Lescar J, Shi PY. Lim SP, et al. Antiviral Res. 2013 Nov;100(2):500-19. doi: 10.1016/j.antiviral.2013.09.013. Epub 2013 Sep 27. Antiviral Res. 2013. PMID: 24076358 Review.

2

West Nile virus drug discovery.

Lim SP, Shi PY. Lim SP, et al. Viruses. 2013 Dec 3;5(12):2977-3006. doi: 10.3390/v5122977. Viruses. 2013. PMID: 24300672 Free PMC article. Review.

3

Polymerases of hepatitis C viruses and flaviviruses: structural and mechanistic insights and drug development.

Caillet-Saguy C, Lim SP, Shi PY, Lescar J, Bressanelli S. Caillet-Saguy C, et al. Among authors: lim sp. Antiviral Res. 2014 May;105:8-16. doi: 10.1016/j.antiviral.2014.02.006. Epub 2014 Feb 19. Antiviral Res. 2014. PMID: 24561230 Review.

4

Stabilization of dengue virus polymerase in de novo initiation assay provides advantages for compound screening.

Niyomrattanakit P, Wan KF, Chung KY, Abas SN, Seh CC, Dong H, Lim CC, Chao AT, Lee CB, Nilar S, Lescar J, Shi PY, Beer D, Lim SP. Niyomrattanakit P, et al. Among authors: lim cc, lim sp. Antiviral Res. 2015 Jul;119:36-46. doi: 10.1016/j.antiviral.2015.04.007. Epub 2015 Apr 18. Antiviral Res. 2015. PMID: 25896272

5

The dengue virus NS5 protein as a target for drug discovery.

Lim SP, Noble CG, Shi PY. Lim SP, et al. Antiviral Res. 2015 Jul;119:57-67. doi: 10.1016/j.antiviral.2015.04.010. Epub 2015 Apr 24. Antiviral Res. 2015. PMID: 25912817 Review.

6

Discovery of Potent Non-Nucleoside Inhibitors of Dengue Viral RNA-Dependent RNA Polymerase from a Fragment Hit Using Structure-Based Drug Design.

Yokokawa F, Nilar S, Noble CG, Lim SP, Rao R, Tania S, Wang G, Lee G, Hunziker J, Karuna R, Manjunatha U, Shi PY, Smith PW. Yokokawa F, et al. Among authors: lim sp. J Med Chem. 2016 Apr 28;59(8):3935-52. doi: 10.1021/acs.jmedchem.6b00143. Epub 2016 Apr 8. J Med Chem. 2016. PMID: 26984786

7

Discovery of Potent Non-nucleoside Inhibitors of Dengue Viral RNA-Dependent RNA Polymerase from Fragment Screening and Structure-Guided Design.

Lim SP, Noble CG, Nilar S, Shi PY, Yokokawa F. Lim SP, et al. Adv Exp Med Biol. 2018;1062:187-198. doi: 10.1007/978-981-10-8727-1_14. Adv Exp Med Biol. 2018. PMID: 29845534 Review.

8

Two RNA Tunnel Inhibitors Bind in Highly Conserved Sites in Dengue Virus NS5 Polymerase: Structural and Functional Studies.

Arora R, Liew CW, Soh TS, Otoo DA, Seh CC, Yue K, Nilar S, Wang G, Yokokawa F, Noble CG, Chen YL, Shi PY, Lescar J, Smith TM, Benson TE, Lim SP. Arora R, et al. Among authors: lim sp. J Virol. 2020 Nov 23;94(24):e01130-20. doi: 10.1128/JVI.01130-20. Print 2020 Nov 23. J Virol. 2020. PMID: 32907977 Free PMC article.

9

NITD-688, a pan-serotype inhibitor of the dengue virus NS4B protein, shows favorable pharmacokinetics and efficacy in preclinical animal models.

Moquin SA, Simon O, Karuna R, Lakshminarayana SB, Yokokawa F, Wang F, Saravanan C, Zhang J, Day CW, Chan K, Wang QY, Lu S, Dong H, Wan KF, Lim SP, Liu W, Seh CC, Chen YL, Xu H, Barkan DT, Kounde CS, Sim WLS, Wang G, Yeo HQ, Zou B, Chan WL, Ding M, Song JG, Li M, Osborne C, Blasco F, Sarko C, Beer D, Bonamy GMC, Sasseville VG, Shi PY, Diagana TT, Yeung BKS, Gu F. Moquin SA, et al. Among authors: lim sp. Sci Transl Med. 2021 Feb 3;13(579):eabb2181. doi: 10.1126/scitranslmed.abb2181. Sci Transl Med. 2021. PMID: 33536278

10

A scintillation proximity assay for dengue virus NS5 2'-O-methyltransferase-kinetic and inhibition analyses.

Lim SP, Wen D, Yap TL, Yan CK, Lescar J, Vasudevan SG. Lim SP, et al. Antiviral Res. 2008 Dec;80(3):360-9. doi: 10.1016/j.antiviral.2008.08.005. Epub 2008 Sep 20. Antiviral Res. 2008. PMID: 18809436

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My NCBI Filters

Text availability

Article attribute

Article type

Publication date

204 results

Search Page