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Cross-species efficacy of enzyme replacement therapy for CLN1 disease in mice and sheep.
Nelvagal HR, Eaton SL, Wang SH, Eultgen EM, Takahashi K, Le SQ, Nesbitt R, Dearborn JT, Siano N, Puhl AC, Dickson PI, Thompson G, Murdoch F, Brennan PM, Gray M, Greenhalgh SN, Tennant P, Gregson R, Clutton E, Nixon J, Proudfoot C, Guido S, Lillico SG, Whitelaw CBA, Lu JY, Hofmann SL, Ekins S, Sands MS, Wishart TM, Cooper JD. Nelvagal HR, et al. Among authors: lillico sg. J Clin Invest. 2022 Oct 17;132(20):e163107. doi: 10.1172/JCI163107. J Clin Invest. 2022. PMID: 36040802 Free PMC article.
Transgenic sheep designed for transplantation studies.
Ritchie WA, King T, Neil C, Carlisle AJ, Lillico S, McLachlan G, Whitelaw CB. Ritchie WA, et al. Mol Reprod Dev. 2009 Jan;76(1):61-4. doi: 10.1002/mrd.20930. Mol Reprod Dev. 2009. PMID: 18449866
Live pigs produced from genome edited zygotes.
Lillico SG, Proudfoot C, Carlson DF, Stverakova D, Neil C, Blain C, King TJ, Ritchie WA, Tan W, Mileham AJ, McLaren DG, Fahrenkrug SC, Whitelaw CB. Lillico SG, et al. Sci Rep. 2013 Oct 10;3:2847. doi: 10.1038/srep02847. Sci Rep. 2013. PMID: 24108318 Free PMC article.
Genome edited sheep and cattle.
Proudfoot C, Carlson DF, Huddart R, Long CR, Pryor JH, King TJ, Lillico SG, Mileham AJ, McLaren DG, Whitelaw CB, Fahrenkrug SC. Proudfoot C, et al. Among authors: lillico sg. Transgenic Res. 2015 Feb;24(1):147-53. doi: 10.1007/s11248-014-9832-x. Epub 2014 Sep 10. Transgenic Res. 2015. PMID: 25204701 Free PMC article.
Highly efficient targeted chromosome deletions using CRISPR/Cas9.
He Z, Proudfoot C, Mileham AJ, McLaren DG, Whitelaw CB, Lillico SG. He Z, et al. Among authors: lillico sg. Biotechnol Bioeng. 2015 May;112(5):1060-4. doi: 10.1002/bit.25490. Epub 2014 Dec 23. Biotechnol Bioeng. 2015. PMID: 25362885
Engineering large animal models of human disease.
Whitelaw CB, Sheets TP, Lillico SG, Telugu BP. Whitelaw CB, et al. Among authors: lillico sg. J Pathol. 2016 Jan;238(2):247-56. doi: 10.1002/path.4648. Epub 2015 Nov 28. J Pathol. 2016. PMID: 26414877 Free PMC article. Review.
Gene targeting, genome editing: from Dolly to editors.
Tan W, Proudfoot C, Lillico SG, Whitelaw CB. Tan W, et al. Among authors: lillico sg. Transgenic Res. 2016 Jun;25(3):273-87. doi: 10.1007/s11248-016-9932-x. Epub 2016 Feb 3. Transgenic Res. 2016. PMID: 26847670 Free PMC article. Review.
Genetically engineering milk.
Whitelaw CB, Joshi A, Kumar S, Lillico SG, Proudfoot C. Whitelaw CB, et al. Among authors: lillico sg. J Dairy Res. 2016 Feb;83(1):3-11. doi: 10.1017/S0022029916000017. J Dairy Res. 2016. PMID: 26869106 Free article. Review.
58 results