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OFraMP: a fragment-based tool to facilitate the parametrization of large molecules.
Stroet M, Caron B, Engler MS, van der Woning J, Kauffmann A, van Dijk M, El-Kebir M, Visscher KM, Holownia J, Macfarlane C, Bennion BJ, Gelpi-Dominguez S, Lightstone FC, van der Storm T, Geerke DP, Mark AE, Klau GW. Stroet M, et al. Among authors: lightstone fc. J Comput Aided Mol Des. 2023 Aug;37(8):357-371. doi: 10.1007/s10822-023-00511-7. Epub 2023 Jun 13. J Comput Aided Mol Des. 2023. PMID: 37310542 Free PMC article.
Pyrrolopyrimidine inhibitors of DNA gyrase B (GyrB) and topoisomerase IV (ParE), Part II: development of inhibitors with broad spectrum, Gram-negative antibacterial activity.
Trzoss M, Bensen DC, Li X, Chen Z, Lam T, Zhang J, Creighton CJ, Cunningham ML, Kwan B, Stidham M, Nelson K, Brown-Driver V, Castellano A, Shaw KJ, Lightstone FC, Wong SE, Nguyen TB, Finn J, Tari LW. Trzoss M, et al. Among authors: lightstone fc. Bioorg Med Chem Lett. 2013 Mar 1;23(5):1537-43. doi: 10.1016/j.bmcl.2012.11.073. Epub 2012 Dec 8. Bioorg Med Chem Lett. 2013. PMID: 23294697
Pharmacokinetic characterization in xenografted mice of a series of first-generation mimics for HLA-DR antibody, Lym-1, as carrier molecules to image and treat lymphoma.
DeNardo GL, Natarajan A, Hok S, Perkins J, Cosman M, DeNardo SJ, Lightstone FC, Mirick GR, Miers LA, Balhorn RL. DeNardo GL, et al. Among authors: lightstone fc. J Nucl Med. 2007 Aug;48(8):1338-47. doi: 10.2967/jnumed.107.041095. Epub 2007 Jul 13. J Nucl Med. 2007. PMID: 17631545 Free article.
Efficient Computational Modeling of Human Ventricular Activation and Its Electrocardiographic Representation: A Sensitivity Study.
Cranford JP, O'Hara TJ, Villongco CT, Hafez OM, Blake RC, Loscalzo J, Fattebert JL, Richards DF, Zhang X, Glosli JN, McCulloch AD, Krummen DE, Lightstone FC, Wong SE. Cranford JP, et al. Among authors: lightstone fc. Cardiovasc Eng Technol. 2018 Sep;9(3):447-467. doi: 10.1007/s13239-018-0347-0. Epub 2018 Mar 16. Cardiovasc Eng Technol. 2018. PMID: 29549620 Free PMC article.
Pyrrolopyrimidine inhibitors of DNA gyrase B (GyrB) and topoisomerase IV (ParE). Part I: Structure guided discovery and optimization of dual targeting agents with potent, broad-spectrum enzymatic activity.
Tari LW, Trzoss M, Bensen DC, Li X, Chen Z, Lam T, Zhang J, Creighton CJ, Cunningham ML, Kwan B, Stidham M, Shaw KJ, Lightstone FC, Wong SE, Nguyen TB, Nix J, Finn J. Tari LW, et al. Among authors: lightstone fc. Bioorg Med Chem Lett. 2013 Mar 1;23(5):1529-36. doi: 10.1016/j.bmcl.2012.11.032. Epub 2012 Dec 5. Bioorg Med Chem Lett. 2013. PMID: 23352267
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