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Investigation into scalable and efficient enterotoxigenic Escherichia coli bacteriophage production.
Sci Rep. 2024 Feb 13;14(1):3618. doi: 10.1038/s41598-024-53276-w.
Sci Rep. 2024.
PMID: 38351153
Free PMC article.
Combining bacteriophage and vancomycin is efficacious against MRSA biofilm-like aggregates formed in synovial fluid.
Taha M, Arnaud T, Lightly TJ, Peters D, Wang L, Chen W, Cook BWM, Theriault SS, Abdelbary H.
Taha M, et al. Among authors: lightly tj.
Front Med (Lausanne). 2023 Jun 9;10:1134912. doi: 10.3389/fmed.2023.1134912. eCollection 2023.
Front Med (Lausanne). 2023.
PMID: 37359001
Free PMC article.
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The Phenylacetic Acid Catabolic Pathway Regulates Antibiotic and Oxidative Stress Responses in Acinetobacter.
Hooppaw AJ, McGuffey JC, Di Venanzio G, Ortiz-Marquez JC, Weber BS, Lightly TJ, van Opijnen T, Scott NE, Cardona ST, Feldman MF.
Hooppaw AJ, et al. Among authors: lightly tj.
mBio. 2022 Jun 28;13(3):e0186321. doi: 10.1128/mbio.01863-21. Epub 2022 Apr 25.
mBio. 2022.
PMID: 35467424
Free PMC article.
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Phenylacetyl Coenzyme A, Not Phenylacetic Acid, Attenuates CepIR-Regulated Virulence in Burkholderia cenocepacia.
Lightly TJ, Frejuk KL, Groleau MC, Chiarelli LR, Ras C, Buroni S, Déziel E, Sorensen JL, Cardona ST.
Lightly TJ, et al.
Appl Environ Microbiol. 2019 Nov 27;85(24):e01594-19. doi: 10.1128/AEM.01594-19. Print 2019 Dec 15.
Appl Environ Microbiol. 2019.
PMID: 31585996
Free PMC article.
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A Broad-Host-Range CRISPRi Toolkit for Silencing Gene Expression in Burkholderia.
Hogan AM, Rahman ASMZ, Lightly TJ, Cardona ST.
Hogan AM, et al. Among authors: lightly tj.
ACS Synth Biol. 2019 Oct 18;8(10):2372-2384. doi: 10.1021/acssynbio.9b00232. Epub 2019 Sep 20.
ACS Synth Biol. 2019.
PMID: 31491085
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Synthetic cystic fibrosis sputum medium diminishes Burkholderia cenocepacia antifungal activity against Aspergillus fumigatus independently of phenylacetic acid production.
Lightly TJ, Phung RR, Sorensen JL, Cardona ST.
Lightly TJ, et al.
Can J Microbiol. 2017 May;63(5):427-438. doi: 10.1139/cjm-2016-0705. Epub 2017 Feb 8.
Can J Microbiol. 2017.
PMID: 28178425
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The attenuated virulence of a Burkholderia cenocepacia paaABCDE mutant is due to inhibition of quorum sensing by release of phenylacetic acid.
Pribytkova T, Lightly TJ, Kumar B, Bernier SP, Sorensen JL, Surette MG, Cardona ST.
Pribytkova T, et al. Among authors: lightly tj.
Mol Microbiol. 2014 Nov;94(3):522-36. doi: 10.1111/mmi.12771. Epub 2014 Sep 19.
Mol Microbiol. 2014.
PMID: 25155974
Free article.
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