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Structure-guided design of pyridoclax derivatives based on Noxa / Mcl-1 interaction mode.
Hedir S, De Giorgi M, Fogha J, De Pascale M, Weiswald LB, Brotin E, Marekha B, Denoyelle C, Denis C, Suzanne P, Gautier F, Juin P, Ligat L, Lopez F, Carlier L, Legay R, Bureau R, Rault S, Poulain L, Oliveira Santos JS, Voisin-Chiret AS. Hedir S, et al. Among authors: ligat l. Eur J Med Chem. 2018 Nov 5;159:357-380. doi: 10.1016/j.ejmech.2018.10.003. Epub 2018 Oct 4. Eur J Med Chem. 2018. PMID: 30308410
Interaction between hormone-sensitive lipase and ChREBP in fat cells controls insulin sensitivity.
Morigny P, Houssier M, Mairal A, Ghilain C, Mouisel E, Benhamed F, Masri B, Recazens E, Denechaud PD, Tavernier G, Caspar-Bauguil S, Virtue S, Sramkova V, Monbrun L, Mazars A, Zanoun M, Guilmeau S, Barquissau V, Beuzelin D, Bonnel S, Marques M, Monge-Roffarello B, Lefort C, Fielding B, Sulpice T, Astrup A, Payrastre B, Bertrand-Michel J, Meugnier E, Ligat L, Lopez F, Guillou H, Ling C, Holm C, Rabasa-Lhoret R, Saris WHM, Stich V, Arner P, Rydén M, Moro C, Viguerie N, Harms M, Hallén S, Vidal-Puig A, Vidal H, Postic C, Langin D. Morigny P, et al. Among authors: ligat l. Nat Metab. 2019 Jan;1(1):133-146. doi: 10.1038/s42255-018-0007-6. Epub 2018 Dec 3. Nat Metab. 2019. PMID: 32694809
Nurse-like cells promote CLL survival through LFA-3/CD2 interactions.
Boissard F, Tosolini M, Ligat L, Quillet-Mary A, Lopez F, Fournié JJ, Ysebaert L, Poupot M. Boissard F, et al. Among authors: ligat l. Oncotarget. 2016 Nov 26;8(32):52225-52236. doi: 10.18632/oncotarget.13660. eCollection 2017 Aug 8. Oncotarget. 2016. PMID: 28881725 Free PMC article.
27 results