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Microglia monitor and protect neuronal function through specialized somatic purinergic junctions.
Cserép C, Pósfai B, Lénárt N, Fekete R, László ZI, Lele Z, Orsolits B, Molnár G, Heindl S, Schwarcz AD, Ujvári K, Környei Z, Tóth K, Szabadits E, Sperlágh B, Baranyi M, Csiba L, Hortobágyi T, Maglóczky Z, Martinecz B, Szabó G, Erdélyi F, Szipőcs R, Tamkun MM, Gesierich B, Duering M, Katona I, Liesz A, Tamás G, Dénes Á. Cserép C, et al. Among authors: liesz a. Science. 2020 Jan 31;367(6477):528-537. doi: 10.1126/science.aax6752. Epub 2019 Dec 12. Science. 2020. PMID: 31831638
Recent progress in translational research on neurovascular and neurodegenerative disorders.
Demuth HU, Dijkhuizen RM, Farr TD, Gelderblom M, Horsburgh K, Iadecola C, Mcleod DD, Michalski D, Murphy TH, Orbe J, Otte WM, Petzold GC, Plesnila N, Reiser G, Reymann KG, Rueger MA, Saur D, Savitz SI, Schilling S, Spratt NJ, Turner RJ, Vemuganti R, Vivien D, Yepes M, Zille M, Boltze J; ISN&N meeting contributors. Demuth HU, et al. Restor Neurol Neurosci. 2017;35(1):87-103. doi: 10.3233/RNN-160690. Restor Neurol Neurosci. 2017. PMID: 28059802 Free PMC article. Review.
Automated Morphological Analysis of Microglia After Stroke.
Heindl S, Gesierich B, Benakis C, Llovera G, Duering M, Liesz A. Heindl S, et al. Among authors: liesz a. Front Cell Neurosci. 2018 Apr 19;12:106. doi: 10.3389/fncel.2018.00106. eCollection 2018. Front Cell Neurosci. 2018. PMID: 29725290 Free PMC article.
The gut microbiome primes a cerebroprotective immune response after stroke.
Singh V, Sadler R, Heindl S, Llovera G, Roth S, Benakis C, Liesz A. Singh V, et al. Among authors: liesz a. J Cereb Blood Flow Metab. 2018 Aug;38(8):1293-1298. doi: 10.1177/0271678X18780130. Epub 2018 May 30. J Cereb Blood Flow Metab. 2018. PMID: 29846130 Free PMC article.
Active poly-GA vaccination prevents microglia activation and motor deficits in a C9orf72 mouse model.
Zhou Q, Mareljic N, Michaelsen M, Parhizkar S, Heindl S, Nuscher B, Farny D, Czuppa M, Schludi C, Graf A, Krebs S, Blum H, Feederle R, Roth S, Haass C, Arzberger T, Liesz A, Edbauer D. Zhou Q, et al. Among authors: liesz a. EMBO Mol Med. 2020 Feb 7;12(2):e10919. doi: 10.15252/emmm.201910919. Epub 2019 Dec 20. EMBO Mol Med. 2020. PMID: 31858749 Free PMC article.
Short-Chain Fatty Acids Improve Poststroke Recovery via Immunological Mechanisms.
Sadler R, Cramer JV, Heindl S, Kostidis S, Betz D, Zuurbier KR, Northoff BH, Heijink M, Goldberg MP, Plautz EJ, Roth S, Malik R, Dichgans M, Holdt LM, Benakis C, Giera M, Stowe AM, Liesz A. Sadler R, et al. Among authors: liesz a. J Neurosci. 2020 Jan 29;40(5):1162-1173. doi: 10.1523/JNEUROSCI.1359-19.2019. Epub 2019 Dec 30. J Neurosci. 2020. PMID: 31889008 Free PMC article.
Loss of TREM2 rescues hyperactivation of microglia, but not lysosomal deficits and neurotoxicity in models of progranulin deficiency.
Reifschneider A, Robinson S, van Lengerich B, Gnörich J, Logan T, Heindl S, Vogt MA, Weidinger E, Riedl L, Wind K, Zatcepin A, Pesämaa I, Haberl S, Nuscher B, Kleinberger G, Klimmt J, Götzl JK, Liesz A, Bürger K, Brendel M, Levin J, Diehl-Schmid J, Suh J, Di Paolo G, Lewcock JW, Monroe KM, Paquet D, Capell A, Haass C. Reifschneider A, et al. Among authors: liesz a. EMBO J. 2022 Feb 15;41(4):e109108. doi: 10.15252/embj.2021109108. Epub 2022 Jan 12. EMBO J. 2022. PMID: 35019161 Free PMC article.
89 results