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In silico prediction of immune-escaping hot spots for future COVID-19 vaccine design.
Sci Rep. 2023 Aug 18;13(1):13468. doi: 10.1038/s41598-023-40741-1.
Sci Rep. 2023.
PMID: 37596329
Free PMC article.
Establishment of extensive artificial intelligence models for kinase inhibitor prediction: Identification of novel PDGFRB inhibitors.
Lien ST, Lin TE, Hsieh JH, Sung TY, Chen JH, Hsu KC.
Lien ST, et al.
Comput Biol Med. 2023 Apr;156:106722. doi: 10.1016/j.compbiomed.2023.106722. Epub 2023 Mar 1.
Comput Biol Med. 2023.
PMID: 36878123
Free article.
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In silico identification and biological evaluation of a selective MAP4K4 inhibitor against pancreatic cancer.
Chang CD, Chao MW, Lee HY, Liu YT, Tu HJ, Lien ST, Lin TE, Sung TY, Yen SC, Huang SH, Hsu KC, Pan SL.
Chang CD, et al. Among authors: lien st.
J Enzyme Inhib Med Chem. 2023 Dec;38(1):2166039. doi: 10.1080/14756366.2023.2166039.
J Enzyme Inhib Med Chem. 2023.
PMID: 36683274
Free PMC article.
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Identification of a dual FLT3 and MNK2 inhibitor for acute myeloid leukemia treatment using a structure-based virtual screening approach.
Yen SC, Chen LC, Huang HL, HuangFu WC, Chen YY, Eight Lin T, Lien ST, Tseng HJ, Sung TY, Hsieh JH, Huang WJ, Pan SL, Hsu KC.
Yen SC, et al. Among authors: lien st.
Bioorg Chem. 2022 Apr;121:105675. doi: 10.1016/j.bioorg.2022.105675. Epub 2022 Feb 11.
Bioorg Chem. 2022.
PMID: 35182882
Free article.
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The Antileukemic Effect of Xestoquinone, A Marine-Derived Polycyclic Quinone-Type Metabolite, Is Mediated through ROS-Induced Inhibition of HSP-90.
Wang KC, Lu MC, Hsu KC, El-Shazly M, Shih SP, Lien ST, Kuo FW, Yang SC, Chen CL, Yang YSH.
Wang KC, et al. Among authors: lien st.
Molecules. 2021 Nov 21;26(22):7037. doi: 10.3390/molecules26227037.
Molecules. 2021.
PMID: 34834129
Free PMC article.
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Investigation of Selected Flavonoid Derivatives as Potent FLT3 Inhibitors for the Potential Treatment of Acute Myeloid Leukemia.
Yen SC, Chen LC, Huang HL, Ngo ST, Wu YW, Lin TE, Sung TY, Lien ST, Tseng HJ, Pan SL, Huang WJ, Hsu KC.
Yen SC, et al. Among authors: lien st.
J Nat Prod. 2021 Jan 22;84(1):1-10. doi: 10.1021/acs.jnatprod.0c00589. Epub 2021 Jan 3.
J Nat Prod. 2021.
PMID: 33393294
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Biological Evaluation of Selected Flavonoids as Inhibitors of MNKs Targeting Acute Myeloid Leukemia.
Chen LC, Huang HL, HuangFu WC, Yen SC, Ngo ST, Wu YW, Lin TE, Sung TY, Lien ST, Tseng HJ, Pan SL, Huang WJ, Hsu KC.
Chen LC, et al. Among authors: lien st.
J Nat Prod. 2020 Oct 23;83(10):2967-2975. doi: 10.1021/acs.jnatprod.0c00516. Epub 2020 Oct 7.
J Nat Prod. 2020.
PMID: 33026809
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Fluoropyrimidin-2,4-dihydroxy-5-isopropylbenzamides as antitumor agents against CRC and NSCLC cancer cells.
Wu WC, Liu YM, Liao YH, Hsu KC, Lien ST, Chen IC, Lai MJ, Li YH, Pan SL, Chen MC, Liou JP.
Wu WC, et al. Among authors: lien st.
Eur J Med Chem. 2020 Oct 1;203:112540. doi: 10.1016/j.ejmech.2020.112540. Epub 2020 Jul 16.
Eur J Med Chem. 2020.
PMID: 32683166
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