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Ras-mutant cancers are sensitive to small molecule inhibition of V-type ATPases in mice.
Tolani B, Celli A, Yao Y, Tan YZ, Fetter R, Liem CR, de Smith AJ, Vasanthakumar T, Bisignano P, Cotton AD, Seiple IB, Rubinstein JL, Jost M, Weissman JS. Tolani B, et al. Among authors: liem cr. Nat Biotechnol. 2022 Dec;40(12):1834-1844. doi: 10.1038/s41587-022-01386-z. Epub 2022 Jul 25. Nat Biotechnol. 2022. PMID: 35879364 Free PMC article.
High-content imaging-based pooled CRISPR screens in mammalian cells.
Yan X, Stuurman N, Ribeiro SA, Tanenbaum ME, Horlbeck MA, Liem CR, Jost M, Weissman JS, Vale RD. Yan X, et al. Among authors: liem cr. J Cell Biol. 2021 Feb 1;220(2):e202008158. doi: 10.1083/jcb.202008158. J Cell Biol. 2021. PMID: 33465779 Free PMC article.