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IL-17A-producing CD8+ T cells promote PDAC via induction of inflammatory cancer-associated fibroblasts.
Picard FSR, Lutz V, Brichkina A, Neuhaus F, Ruckenbrod T, Hupfer A, Raifer H, Klein M, Bopp T, Pfefferle PI, Savai R, Prinz I, Waisman A, Moos S, Chang HD, Heinrich S, Bartsch DK, Buchholz M, Singh S, Tu M, Klein L, Bauer C, Liefke R, Burchert A, Chung HR, Mayer P, Gress TM, Lauth M, Gaida M, Huber M. Picard FSR, et al. Among authors: liefke r. Gut. 2023 Aug;72(8):1510-1522. doi: 10.1136/gutjnl-2022-327855. Epub 2023 Feb 9. Gut. 2023. PMID: 36759154 Free PMC article.
Biochemical Features of Recombinant Human Cyclophilin J.
Chen J, Liefke R, Jiang L, Wang J, Huang C, Gong Z, Schiene-Fischer C, Yu L. Chen J, et al. Among authors: liefke r. Anticancer Res. 2016 Mar;36(3):1175-80. Anticancer Res. 2016. PMID: 26977013
Phf19 links methylated Lys36 of histone H3 to regulation of Polycomb activity.
Ballaré C, Lange M, Lapinaite A, Martin GM, Morey L, Pascual G, Liefke R, Simon B, Shi Y, Gozani O, Carlomagno T, Benitah SA, Di Croce L. Ballaré C, et al. Among authors: liefke r. Nat Struct Mol Biol. 2012 Dec;19(12):1257-65. doi: 10.1038/nsmb.2434. Epub 2012 Oct 28. Nat Struct Mol Biol. 2012. PMID: 23104054 Free PMC article.
Polycomb-like proteins link the PRC2 complex to CpG islands.
Li H, Liefke R, Jiang J, Kurland JV, Tian W, Deng P, Zhang W, He Q, Patel DJ, Bulyk ML, Shi Y, Wang Z. Li H, et al. Among authors: liefke r. Nature. 2017 Sep 14;549(7671):287-291. doi: 10.1038/nature23881. Epub 2017 Sep 6. Nature. 2017. PMID: 28869966 Free PMC article.
Ush regulates hemocyte-specific gene expression, fatty acid metabolism and cell cycle progression and cooperates with dNuRD to orchestrate hematopoiesis.
Lenz J, Liefke R, Funk J, Shoup S, Nist A, Stiewe T, Schulz R, Tokusumi Y, Albert L, Raifer H, Förstemann K, Vázquez O, Tokusumi T, Fossett N, Brehm A. Lenz J, et al. Among authors: liefke r. PLoS Genet. 2021 Feb 18;17(2):e1009318. doi: 10.1371/journal.pgen.1009318. eCollection 2021 Feb. PLoS Genet. 2021. PMID: 33600407 Free PMC article.
NF-κB p65 dimerization and DNA-binding is important for inflammatory gene expression.
Riedlinger T, Liefke R, Meier-Soelch J, Jurida L, Nist A, Stiewe T, Kracht M, Schmitz ML. Riedlinger T, et al. Among authors: liefke r. FASEB J. 2019 Mar;33(3):4188-4202. doi: 10.1096/fj.201801638R. Epub 2018 Dec 7. FASEB J. 2019. PMID: 30526044 Free PMC article.
This suggests a mechanism of assisted p65 chromatin association that can be in part facilitated by chromatin priming and cooperativity with other transcription factors such as AP-1.-Riedlinger, T., Liefke, R., Meier-Soelch, J., Jurida, L., Nist, A., Stiewe, T., Krac …
This suggests a mechanism of assisted p65 chromatin association that can be in part facilitated by chromatin priming and cooperativity with …
Polycomb-like Proteins in Gene Regulation and Cancer.
Fischer S, Liefke R. Fischer S, et al. Among authors: liefke r. Genes (Basel). 2023 Apr 18;14(4):938. doi: 10.3390/genes14040938. Genes (Basel). 2023. PMID: 37107696 Free PMC article. Review.
28 results