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Gut microbiota-derived metabolites confer protection against SARS-CoV-2 infection.
Brown JA, Sanidad KZ, Lucotti S, Lieber CM, Cox RM, Ananthanarayanan A, Basu S, Chen J, Shan M, Amir M, Schmidt F, Weisblum Y, Cioffi M, Li T, Rowdo FM, Martin ML, Guo CJ, Lyssiotis C, Layden BT, Dannenberg AJ, Bieniasz PD, Lee B, Inohara N, Matei I, Plemper RK, Zeng MY. Brown JA, et al. Among authors: lieber cm. Gut Microbes. 2022 Jan-Dec;14(1):2105609. doi: 10.1080/19490976.2022.2105609. Gut Microbes. 2022. PMID: 35915556 Free PMC article.
Oral prodrug of remdesivir parent GS-441524 is efficacious against SARS-CoV-2 in ferrets.
Cox RM, Wolf JD, Lieber CM, Sourimant J, Lin MJ, Babusis D, DuPont V, Chan J, Barrett KT, Lye D, Kalla R, Chun K, Mackman RL, Ye C, Cihlar T, Martinez-Sobrido L, Greninger AL, Bilello JP, Plemper RK. Cox RM, et al. Among authors: lieber cm. Nat Commun. 2021 Nov 5;12(1):6415. doi: 10.1038/s41467-021-26760-4. Nat Commun. 2021. PMID: 34741049 Free PMC article.
4'-Fluorouridine is an oral antiviral that blocks respiratory syncytial virus and SARS-CoV-2 replication.
Sourimant J, Lieber CM, Aggarwal M, Cox RM, Wolf JD, Yoon JJ, Toots M, Ye C, Sticher Z, Kolykhalov AA, Martinez-Sobrido L, Bluemling GR, Natchus MG, Painter GR, Plemper RK. Sourimant J, et al. Among authors: lieber cm. Science. 2022 Jan 14;375(6577):161-167. doi: 10.1126/science.abj5508. Epub 2021 Dec 2. Science. 2022. PMID: 34855509 Free PMC article.
4'-Fluorouridine mitigates lethal infection with pandemic human and highly pathogenic avian influenza viruses.
Lieber CM, Aggarwal M, Yoon JJ, Cox RM, Kang HJ, Sourimant J, Toots M, Johnson SK, Jones CA, Sticher ZM, Kolykhalov AA, Saindane MT, Tompkins SM, Planz O, Painter GR, Natchus MG, Sakamoto K, Plemper RK. Lieber CM, et al. PLoS Pathog. 2023 Apr 17;19(4):e1011342. doi: 10.1371/journal.ppat.1011342. eCollection 2023 Apr. PLoS Pathog. 2023. PMID: 37068076 Free PMC article.
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[No authors listed] [No authors listed] PMID: 37433190
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[No authors listed] [No authors listed] PMID: 37449821
235 results