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Activated microglia drive demyelination via CSF1R signaling.
Marzan DE, Brügger-Verdon V, West BL, Liddelow S, Samanta J, Salzer JL. Marzan DE, et al. Among authors: liddelow s. Glia. 2021 Jun;69(6):1583-1604. doi: 10.1002/glia.23980. Epub 2021 Feb 23. Glia. 2021. PMID: 33620118 Free PMC article.
Repurposing the cardiac glycoside digoxin to stimulate myelin regeneration in chemically-induced and immune-mediated mouse models of multiple sclerosis.
Titus HE, Xu H, Robinson AP, Patel PA, Chen Y, Fantini D, Eaton V, Karl M, Garrison ED, Rose IVL, Chiang MY, Podojil JR, Balabanov R, Liddelow SA, Miller RH, Popko B, Miller SD. Titus HE, et al. Glia. 2022 Oct;70(10):1950-1970. doi: 10.1002/glia.24231. Epub 2022 Jul 9. Glia. 2022. PMID: 35809238 Free PMC article.
Astrocytes and microglia: Models and tools.
Guttenplan KA, Liddelow SA. Guttenplan KA, et al. J Exp Med. 2019 Jan 7;216(1):71-83. doi: 10.1084/jem.20180200. Epub 2018 Dec 12. J Exp Med. 2019. PMID: 30541903 Free PMC article. Review.
Neurotoxic reactive astrocytes are induced by activated microglia.
Liddelow SA, Guttenplan KA, Clarke LE, Bennett FC, Bohlen CJ, Schirmer L, Bennett ML, Münch AE, Chung WS, Peterson TC, Wilton DK, Frouin A, Napier BA, Panicker N, Kumar M, Buckwalter MS, Rowitch DH, Dawson VL, Dawson TM, Stevens B, Barres BA. Liddelow SA, et al. Nature. 2017 Jan 26;541(7638):481-487. doi: 10.1038/nature21029. Epub 2017 Jan 18. Nature. 2017. PMID: 28099414 Free PMC article.
Methotrexate Chemotherapy Induces Persistent Tri-glial Dysregulation that Underlies Chemotherapy-Related Cognitive Impairment.
Gibson EM, Nagaraja S, Ocampo A, Tam LT, Wood LS, Pallegar PN, Greene JJ, Geraghty AC, Goldstein AK, Ni L, Woo PJ, Barres BA, Liddelow S, Vogel H, Monje M. Gibson EM, et al. Among authors: liddelow s. Cell. 2019 Jan 10;176(1-2):43-55.e13. doi: 10.1016/j.cell.2018.10.049. Epub 2018 Dec 6. Cell. 2019. PMID: 30528430 Free PMC article.
Complement 3+-astrocytes are highly abundant in prion diseases, but their abolishment led to an accelerated disease course and early dysregulation of microglia.
Hartmann K, Sepulveda-Falla D, Rose IVL, Madore C, Muth C, Matschke J, Butovsky O, Liddelow S, Glatzel M, Krasemann S. Hartmann K, et al. Among authors: liddelow s. Acta Neuropathol Commun. 2019 May 22;7(1):83. doi: 10.1186/s40478-019-0735-1. Acta Neuropathol Commun. 2019. PMID: 31118110 Free PMC article.
92 results