Lichtenthaler SF - Search Results

1

ADAM10 and ADAM17 promote SARS-CoV-2 cell entry and spike protein-mediated lung cell fusion.

Jocher G, Grass V, Tschirner SK, Riepler L, Breimann S, Kaya T, Oelsner M, Hamad MS, Hofmann LI, Blobel CP, Schmidt-Weber CB, Gokce O, Jakwerth CA, Trimpert J, Kimpel J, Pichlmair A, Lichtenthaler SF. Jocher G, et al. Among authors: lichtenthaler sf. EMBO Rep. 2022 Jun 7;23(6):e54305. doi: 10.15252/embr.202154305. Epub 2022 May 8. EMBO Rep. 2022. PMID: 35527514 Free PMC article.

2

ADAM10 is the physiologically relevant, constitutive alpha-secretase of the amyloid precursor protein in primary neurons.

Kuhn PH, Wang H, Dislich B, Colombo A, Zeitschel U, Ellwart JW, Kremmer E, Rossner S, Lichtenthaler SF. Kuhn PH, et al. Among authors: lichtenthaler sf. EMBO J. 2010 Sep 1;29(17):3020-32. doi: 10.1038/emboj.2010.167. Epub 2010 Jul 30. EMBO J. 2010. PMID: 20676056 Free PMC article.

3

Determination of the proteolytic cleavage sites of the amyloid precursor-like protein 2 by the proteases ADAM10, BACE1 and γ-secretase.

Hogl S, Kuhn PH, Colombo A, Lichtenthaler SF. Hogl S, et al. Among authors: lichtenthaler sf. PLoS One. 2011;6(6):e21337. doi: 10.1371/journal.pone.0021337. Epub 2011 Jun 17. PLoS One. 2011. PMID: 21695060 Free PMC article.

4

Secretome protein enrichment identifies physiological BACE1 protease substrates in neurons.

Kuhn PH, Koroniak K, Hogl S, Colombo A, Zeitschel U, Willem M, Volbracht C, Schepers U, Imhof A, Hoffmeister A, Haass C, Roßner S, Bräse S, Lichtenthaler SF. Kuhn PH, et al. Among authors: lichtenthaler sf. EMBO J. 2012 Jun 22;31(14):3157-68. doi: 10.1038/emboj.2012.173. EMBO J. 2012. PMID: 22728825 Free PMC article.

5

iRhoms in the brain - a new frontier?

Lichtenthaler SF, O'Hara BF, Blobel CP. Lichtenthaler SF, et al. Cell Cycle. 2015;14(19):3003-4. doi: 10.1080/15384101.2015.1084187. Cell Cycle. 2015. PMID: 26291882 Free PMC article. No abstract available.

6

The alpha secretase ADAM10: A metalloprotease with multiple functions in the brain.

Saftig P, Lichtenthaler SF. Saftig P, et al. Among authors: lichtenthaler sf. Prog Neurobiol. 2015 Dec;135:1-20. doi: 10.1016/j.pneurobio.2015.10.003. Epub 2015 Oct 29. Prog Neurobiol. 2015. PMID: 26522965 Review.

7

Systematic substrate identification indicates a central role for the metalloprotease ADAM10 in axon targeting and synapse function.

Kuhn PH, Colombo AV, Schusser B, Dreymueller D, Wetzel S, Schepers U, Herber J, Ludwig A, Kremmer E, Montag D, Müller U, Schweizer M, Saftig P, Bräse S, Lichtenthaler SF. Kuhn PH, et al. Among authors: lichtenthaler sf. Elife. 2016 Jan 23;5:e12748. doi: 10.7554/eLife.12748. Elife. 2016. PMID: 26802628 Free PMC article.

8

An Alzheimer-associated TREM2 variant occurs at the ADAM cleavage site and affects shedding and phagocytic function.

Schlepckow K, Kleinberger G, Fukumori A, Feederle R, Lichtenthaler SF, Steiner H, Haass C. Schlepckow K, et al. Among authors: lichtenthaler sf. EMBO Mol Med. 2017 Oct;9(10):1356-1365. doi: 10.15252/emmm.201707672. EMBO Mol Med. 2017. PMID: 28855300 Free PMC article.

9

The metalloprotease ADAM10 (a disintegrin and metalloprotease 10) undergoes rapid, postlysis autocatalytic degradation.

Brummer T, Pigoni M, Rossello A, Wang H, Noy PJ, Tomlinson MG, Blobel CP, Lichtenthaler SF. Brummer T, et al. Among authors: lichtenthaler sf. FASEB J. 2018 Jul;32(7):3560-3573. doi: 10.1096/fj.201700823RR. Epub 2018 Feb 7. FASEB J. 2018. PMID: 29430990 Free PMC article.

10

Non-cell-autonomous function of DR6 in Schwann cell proliferation.

Colombo A, Hsia HE, Wang M, Kuhn PH, Brill MS, Canevazzi P, Feederle R, Taveggia C, Misgeld T, Lichtenthaler SF. Colombo A, et al. Among authors: lichtenthaler sf. EMBO J. 2018 Apr 3;37(7):e97390. doi: 10.15252/embj.201797390. Epub 2018 Feb 19. EMBO J. 2018. PMID: 29459438 Free PMC article.

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