Liberante FG - Search Results

1

Biomolecular condensation of NUP98 fusion proteins drives leukemogenic gene expression.

Terlecki-Zaniewicz S, Humer T, Eder T, Schmoellerl J, Heyes E, Manhart G, Kuchynka N, Parapatics K, Liberante FG, Müller AC, Tomazou EM, Grebien F. Terlecki-Zaniewicz S, et al. Among authors: liberante fg. Nat Struct Mol Biol. 2021 Feb;28(2):190-201. doi: 10.1038/s41594-020-00550-w. Epub 2021 Jan 21. Nat Struct Mol Biol. 2021. PMID: 33479542 Free PMC article.

2

Altered splicing and cytoplasmic levels of tRNA synthetases in SF3B1-mutant myelodysplastic syndromes as a therapeutic vulnerability.

Liberante FG, Lappin K, Barros EM, Vohhodina J, Grebien F, Savage KI, Mills KI. Liberante FG, et al. Sci Rep. 2019 Feb 25;9(1):2678. doi: 10.1038/s41598-019-39591-7. Sci Rep. 2019. PMID: 30804405 Free PMC article.

3

Cryptic splicing events in the iron transporter ABCB7 and other key target genes in SF3B1-mutant myelodysplastic syndromes.

Dolatshad H, Pellagatti A, Liberante FG, Llorian M, Repapi E, Steeples V, Roy S, Scifo L, Armstrong RN, Shaw J, Yip BH, Killick S, Kušec R, Taylor S, Mills KI, Savage KI, Smith CW, Boultwood J. Dolatshad H, et al. Among authors: liberante fg. Leukemia. 2016 Dec;30(12):2322-2331. doi: 10.1038/leu.2016.149. Epub 2016 May 23. Leukemia. 2016. PMID: 27211273 Free PMC article.

4

Identification and validation of the dopamine agonist bromocriptine as a novel therapy for high-risk myelodysplastic syndromes and secondary acute myeloid leukemia.

Liberante FG, Pouryahya T, McMullin MF, Zhang SD, Mills KI. Liberante FG, et al. Oncotarget. 2016 Feb 9;7(6):6609-19. doi: 10.18632/oncotarget.6773. Oncotarget. 2016. PMID: 26735888 Free PMC article.

5

Cancer-Associated SF3B1 Mutations Confer a BRCA-Like Cellular Phenotype and Synthetic Lethality to PARP Inhibitors.

Lappin KM, Barros EM, Jhujh SS, Irwin GW, McMillan H, Liberante FG, Latimer C, La Bonte MJ, Mills KI, Harkin DP, Stewart GS, Savage KI. Lappin KM, et al. Among authors: liberante fg. Cancer Res. 2022 Mar 1;82(5):819-830. doi: 10.1158/0008-5472.CAN-21-1843. Cancer Res. 2022. PMID: 35027467 Free PMC article.

6

Chronic loss of STAG2 leads to altered chromatin structure contributing to de-regulated transcription in AML.

Smith JS, Lappin KM, Craig SG, Liberante FG, Crean CM, McDade SS, Thompson A, Mills KI, Savage KI. Smith JS, et al. Among authors: liberante fg. J Transl Med. 2020 Sep 3;18(1):339. doi: 10.1186/s12967-020-02500-y. J Transl Med. 2020. PMID: 32883299 Free PMC article.

7

The RNA processing factors THRAP3 and BCLAF1 promote the DNA damage response through selective mRNA splicing and nuclear export.

Vohhodina J, Barros EM, Savage AL, Liberante FG, Manti L, Bankhead P, Cosgrove N, Madden AF, Harkin DP, Savage KI. Vohhodina J, et al. Among authors: liberante fg. Nucleic Acids Res. 2017 Dec 15;45(22):12816-12833. doi: 10.1093/nar/gkx1046. Nucleic Acids Res. 2017. PMID: 29112714 Free PMC article.

8

Integrated analysis of the molecular action of Vorinostat identifies epi-sensitised targets for combination therapy.

Hay JF, Lappin K, Liberante F, Kettyle LM, Matchett KB, Thompson A, Mills KI. Hay JF, et al. Oncotarget. 2017 Jul 1;8(40):67891-67903. doi: 10.18632/oncotarget.18910. eCollection 2017 Sep 15. Oncotarget. 2017. PMID: 28978082 Free PMC article.

9

The histone deacetylase inhibitor Romidepsin induces as a cascade of differential gene expression and altered histone H3K9 marks in myeloid leukaemia cells.

Clarke K, Young C, Liberante F, McMullin MF, Thompson A, Mills K. Clarke K, et al. Oncotarget. 2019 May 28;10(37):3462-3471. doi: 10.18632/oncotarget.26877. eCollection 2019 May 28. Oncotarget. 2019. PMID: 31191819 Free PMC article.

10

Rational drug repurposing using sscMap analysis in a HOX-TALE model of leukemia.

Kettyle LM, Liberante FG, Thompson A. Kettyle LM, et al. Among authors: liberante fg. Methods Mol Biol. 2014;1196:349-70. doi: 10.1007/978-1-4939-1242-1_21. Methods Mol Biol. 2014. PMID: 25151174

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