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Bile acid sequestration reverses liver injury and prevents progression of nonalcoholic steatohepatitis in Western diet-fed mice.
Takahashi S, Luo Y, Ranjit S, Xie C, Libby AE, Orlicky DJ, Dvornikov A, Wang XX, Myakala K, Jones BA, Bhasin K, Wang D, McManaman JL, Krausz KW, Gratton E, Ir D, Robertson CE, Frank DN, Gonzalez FJ, Levi M. Takahashi S, et al. Among authors: libby ae. J Biol Chem. 2020 Apr 3;295(14):4733-4747. doi: 10.1074/jbc.RA119.011913. Epub 2020 Feb 19. J Biol Chem. 2020. PMID: 32075905 Free PMC article.
The role of FXR and TGR5 in reversing and preventing progression of Western diet-induced hepatic steatosis, inflammation, and fibrosis in mice.
Wang XX, Xie C, Libby AE, Ranjit S, Levi J, Myakala K, Bhasin K, Jones BA, Orlicky DJ, Takahashi S, Dvornikov A, Kleiner DE, Hewitt SM, Adorini L, Kopp JB, Krausz KW, Rosenberg A, McManaman JL, Robertson CE, Ir D, Frank DN, Luo Y, Gonzalez FJ, Gratton E, Levi M. Wang XX, et al. Among authors: libby ae. J Biol Chem. 2022 Nov;298(11):102530. doi: 10.1016/j.jbc.2022.102530. Epub 2022 Oct 7. J Biol Chem. 2022. PMID: 36209823 Free PMC article.
Oral N-acetylcysteine decreases IFN-γ production and ameliorates ischemia-reperfusion injury in steatotic livers.
Liggett JR, Kang J, Ranjit S, Rodriguez O, Loh K, Patil D, Cui Y, Duttargi A, Nguyen S, He B, Lee Y, Oza K, Frank BS, Kwon D, Li HH, Kallakury B, Libby A, Levi M, Robson SC, Fishbein TM, Cui W, Albanese C, Khan K, Kroemer A. Liggett JR, et al. Front Immunol. 2022 Sep 5;13:898799. doi: 10.3389/fimmu.2022.898799. eCollection 2022. Front Immunol. 2022. PMID: 36148239 Free PMC article.
20 results