Libardo MD - Search Results

1

Copper-binding tripeptide motif increases potency of the antimicrobial peptide Anoplin via Reactive Oxygen Species generation.

Libardo MD, Nagella S, Lugo A, Pierce S, Angeles-Boza AM. Libardo MD, et al. Biochem Biophys Res Commun. 2015 Jan 2;456(1):446-51. doi: 10.1016/j.bbrc.2014.11.104. Epub 2014 Dec 4. Biochem Biophys Res Commun. 2015. PMID: 25482446

2

Hybrid peptide ATCUN-sh-Buforin: Influence of the ATCUN charge and stereochemistry on antimicrobial activity.

Libardo MD, Paul TJ, Prabhakar R, Angeles-Boza AM. Libardo MD, et al. Biochimie. 2015 Jun;113:143-55. doi: 10.1016/j.biochi.2015.04.008. Epub 2015 Apr 17. Biochimie. 2015. PMID: 25891844

3

Central Role of the Copper-Binding Motif in the Complex Mechanism of Action of Ixosin: Enhancing Oxidative Damage and Promoting Synergy with Ixosin B.

Libardo MD, Gorbatyuk VY, Angeles-Boza AM. Libardo MD, et al. ACS Infect Dis. 2016 Jan 8;2(1):71-81. doi: 10.1021/acsinfecdis.5b00140. Epub 2015 Dec 14. ACS Infect Dis. 2016. PMID: 27622949

4

Membrane Oxidation in Cell Delivery and Cell Killing Applications.

Wang TY, Libardo MDJ, Angeles-Boza AM, Pellois JP. Wang TY, et al. ACS Chem Biol. 2017 May 19;12(5):1170-1182. doi: 10.1021/acschembio.7b00237. Epub 2017 Apr 10. ACS Chem Biol. 2017. PMID: 28355059 Free PMC article. Review.

5

How Does Membrane Oxidation Affect Cell Delivery and Cell Killing?

Libardo MDJ, Wang TY, Pellois JP, Angeles-Boza AM. Libardo MDJ, et al. Trends Biotechnol. 2017 Aug;35(8):686-690. doi: 10.1016/j.tibtech.2017.03.015. Epub 2017 Apr 28. Trends Biotechnol. 2017. PMID: 28460718 Free PMC article.

6

Nuclease activity gives an edge to host-defense peptide piscidin 3 over piscidin 1, rendering it more effective against persisters and biofilms.

Libardo MDJ, Bahar AA, Ma B, Fu R, McCormick LE, Zhao J, McCallum SA, Nussinov R, Ren D, Angeles-Boza AM, Cotten ML. Libardo MDJ, et al. FEBS J. 2017 Nov;284(21):3662-3683. doi: 10.1111/febs.14263. Epub 2017 Sep 30. FEBS J. 2017. PMID: 28892294 Free PMC article.

7

Phagosomal Copper-Promoted Oxidative Attack on Intracellular Mycobacterium tuberculosis.

Libardo MDJ, de la Fuente-Nuñez C, Anand K, Krishnamoorthy G, Kaiser P, Pringle SC, Dietz C, Pierce S, Smith MB, Barczak A, Kaufmann SHE, Singh A, Angeles-Boza AM. Libardo MDJ, et al. ACS Infect Dis. 2018 Nov 9;4(11):1623-1634. doi: 10.1021/acsinfecdis.8b00171. Epub 2018 Sep 6. ACS Infect Dis. 2018. PMID: 30141623

8

Antimicrobial Peptides and Copper(II) Ions: Novel Therapeutic Opportunities.

Portelinha J, Duay SS, Yu SI, Heilemann K, Libardo MDJ, Juliano SA, Klassen JL, Angeles-Boza AM. Portelinha J, et al. Among authors: libardo mdj. Chem Rev. 2021 Feb 24;121(4):2648-2712. doi: 10.1021/acs.chemrev.0c00921. Epub 2021 Feb 1. Chem Rev. 2021. PMID: 33524257 Review.

9

Copper-binding anticancer peptides from the piscidin family: an expanded mechanism that encompasses physical and chemical bilayer disruption.

Comert F, Heinrich F, Chowdhury A, Schoeneck M, Darling C, Anderson KW, Libardo MDJ, Angeles-Boza AM, Silin V, Cotten ML, Mihailescu M. Comert F, et al. Among authors: libardo mdj. Sci Rep. 2021 Jun 16;11(1):12620. doi: 10.1038/s41598-021-91670-w. Sci Rep. 2021. PMID: 34135370 Free PMC article.

10

Complementary Effects of Host Defense Peptides Piscidin 1 and Piscidin 3 on DNA and Lipid Membranes: Biophysical Insights into Contrasting Biological Activities.

Hayden RM, Goldberg GK, Ferguson BM, Schoeneck MW, Libardo MD, Mayeux SE, Shrestha A, Bogardus KA, Hammer J, Pryshchep S, Lehman HK, McCormick ML, Blazyk J, Angeles-Boza AM, Fu R, Cotten ML. Hayden RM, et al. Among authors: libardo md. J Phys Chem B. 2015 Dec 10;119(49):15235-46. doi: 10.1021/acs.jpcb.5b09685. Epub 2015 Dec 1. J Phys Chem B. 2015. PMID: 26569483

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