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Mi-2β promotes immune evasion in melanoma by activating EZH2 methylation.
Li C, Wang Z, Yao L, Lin X, Jian Y, Li Y, Zhang J, Shao J, Tran PD, Hagman JR, Cao M, Cong Y, Li HY, Goding CR, Xu ZX, Liao X, Miao X, Cui R. Li C, et al. Among authors: liao x. Nat Commun. 2024 Mar 9;15(1):2163. doi: 10.1038/s41467-024-46422-5. Nat Commun. 2024. PMID: 38461299 Free PMC article.
Biochemistry and structural studies of kynurenine 3-monooxygenase reveal allosteric inhibition by Ro 61-8048.
Gao J, Yao L, Xia T, Liao X, Zhu D, Xiang Y. Gao J, et al. Among authors: liao x. FASEB J. 2018 Apr;32(4):2036-2045. doi: 10.1096/fj.201700397RR. Epub 2018 Jan 5. FASEB J. 2018. PMID: 29208702
The unique binding sites distinguish Ro 61-8048 as a noncompetitive and highly selective inhibitor from other competitive inhibitors, which should facilitate further optimization of Ro 61-8048 and the development of new inhibitory drugs to hKMO.-Gao, J., Yao, L., Xia, T., Liao …
The unique binding sites distinguish Ro 61-8048 as a noncompetitive and highly selective inhibitor from other competitive inhibitors, which …
Enhancing KDM5A and TLR activity improves the response to immune checkpoint blockade.
Wang L, Gao Y, Zhang G, Li D, Wang Z, Zhang J, Hermida LC, He L, Wang Z, Si J, Geng S, Ai R, Ning F, Cheng C, Deng H, Dimitrov DS, Sun Y, Huang Y, Wang D, Hu X, Wei Z, Wang W, Liao X. Wang L, et al. Among authors: liao x. Sci Transl Med. 2020 Sep 9;12(560):eaax2282. doi: 10.1126/scitranslmed.aax2282. Sci Transl Med. 2020. PMID: 32908002
7,058 results