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TGFβ2 and TGFβ3 isoforms drive fibrotic disease pathogenesis.
Sun T, Huang Z, Liang WC, Yin J, Lin WY, Wu J, Vernes JM, Lutman J, Caplazi P, Jeet S, Wong T, Wong M, DePianto DJ, Morshead KB, Sun KH, Modrusan Z, Vander Heiden JA, Abbas AR, Zhang H, Xu M, N'Diaye EN, Roose-Girma M, Wolters PJ, Yadav R, Sukumaran S, Ghilardi N, Corpuz R, Emson C, Meng YG, Ramalingam TR, Lupardus P, Brightbill HD, Seshasayee D, Wu Y, Arron JR. Sun T, et al. Among authors: liang wc. Sci Transl Med. 2021 Aug 4;13(605):eabe0407. doi: 10.1126/scitranslmed.abe0407. Sci Transl Med. 2021. PMID: 34349032
Structural studies of neuropilin/antibody complexes provide insights into semaphorin and VEGF binding.
Appleton BA, Wu P, Maloney J, Yin J, Liang WC, Stawicki S, Mortara K, Bowman KK, Elliott JM, Desmarais W, Bazan JF, Bagri A, Tessier-Lavigne M, Koch AW, Wu Y, Watts RJ, Wiesmann C. Appleton BA, et al. Among authors: liang wc. EMBO J. 2007 Nov 28;26(23):4902-12. doi: 10.1038/sj.emboj.7601906. Epub 2007 Nov 8. EMBO J. 2007. PMID: 17989695 Free PMC article.
Structural insight into distinct mechanisms of protease inhibition by antibodies.
Wu Y, Eigenbrot C, Liang WC, Stawicki S, Shia S, Fan B, Ganesan R, Lipari MT, Kirchhofer D. Wu Y, et al. Among authors: liang wc. Proc Natl Acad Sci U S A. 2007 Dec 11;104(50):19784-9. doi: 10.1073/pnas.0708251104. Epub 2007 Dec 5. Proc Natl Acad Sci U S A. 2007. PMID: 18077410 Free PMC article.
Antixenograft tumor activity of a humanized anti-insulin-like growth factor-I receptor monoclonal antibody is associated with decreased AKT activation and glucose uptake.
Shang Y, Mao Y, Batson J, Scales SJ, Phillips G, Lackner MR, Totpal K, Williams S, Yang J, Tang Z, Modrusan Z, Tan C, Liang WC, Tsai SP, Vanderbilt A, Kozuka K, Hoeflich K, Tien J, Ross S, Li C, Lee SH, Song A, Wu Y, Stephan JP, Ashkenazi A, Zha J. Shang Y, et al. Among authors: liang wc. Mol Cancer Ther. 2008 Sep;7(9):2599-608. doi: 10.1158/1535-7163.MCT-07-2401. Mol Cancer Ther. 2008. PMID: 18790743
Function of CSF1 and IL34 in Macrophage Homeostasis, Inflammation, and Cancer.
Lin W, Xu D, Austin CD, Caplazi P, Senger K, Sun Y, Jeet S, Young J, Delarosa D, Suto E, Huang Z, Zhang J, Yan D, Corzo C, Barck K, Rajan S, Looney C, Gandham V, Lesch J, Liang WC, Mai E, Ngu H, Ratti N, Chen Y, Misner D, Lin T, Danilenko D, Katavolos P, Doudemont E, Uppal H, Eastham J, Mak J, de Almeida PE, Bao K, Hadadianpour A, Keir M, Carano RAD, Diehl L, Xu M, Wu Y, Weimer RM, DeVoss J, Lee WP, Balazs M, Walsh K, Alatsis KR, Martin F, Zarrin AA. Lin W, et al. Among authors: liang wc. Front Immunol. 2019 Sep 4;10:2019. doi: 10.3389/fimmu.2019.02019. eCollection 2019. Front Immunol. 2019. PMID: 31552020 Free PMC article.
Harnessing MerTK agonism for targeted therapeutics.
Kedage V, Ellerman D, Chen Y, Liang WC, Borneo J, Wu Y, Yan M. Kedage V, et al. Among authors: liang wc. MAbs. 2020 Jan-Dec;12(1):1685832. doi: 10.1080/19420862.2019.1685832. MAbs. 2020. PMID: 31852344 Free PMC article.
143 results