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CD8+ lymphocytes do not impact SIV reservoir establishment under ART.
Statzu M, Jin W, Fray EJ, Wong AKH, Kumar MR, Ferrer E, Docken SS, Pinkevych M, McBrien JB, Fennessey CM, Keele BF, Liang S, Harper JL, Mutascio S, Franchitti L, Wang H, Cicetti D, Bosinger SE, Carnathan DG, Vanderford TH, Margolis DM, Garcia-Martinez JV, Chahroudi A, Paiardini M, Siliciano J, Davenport MP, Kulpa DA, Siliciano RS, Silvestri G. Statzu M, et al. Among authors: liang s. Nat Microbiol. 2023 Feb;8(2):299-308. doi: 10.1038/s41564-022-01311-9. Epub 2023 Jan 23. Nat Microbiol. 2023. PMID: 36690860 Free PMC article.
Simian-Human Immunodeficiency Virus SHIV.C.CH505 Persistence in ART-Suppressed Infant Macaques Is Characterized by Elevated SHIV RNA in the Gut and a High Abundance of Intact SHIV DNA in Naive CD4+ T Cells.
Obregon-Perko V, Bricker KM, Mensah G, Uddin F, Kumar MR, Fray EJ, Siliciano RF, Schoof N, Horner A, Mavigner M, Liang S, Vanderford T, Sass J, Chan C, Berendam SJ, Bar KJ, Shaw GM, Silvestri G, Fouda GG, Permar SR, Chahroudi A. Obregon-Perko V, et al. Among authors: liang s. J Virol. 2020 Dec 22;95(2):e01669-20. doi: 10.1128/JVI.01669-20. Print 2020 Dec 22. J Virol. 2020. PMID: 33087463 Free PMC article.
Altered Response Pattern following AZD5582 Treatment of SIV-Infected, ART-Suppressed Rhesus Macaque Infants.
Bricker KM, Obregon-Perko V, Williams B, Oliver D, Uddin F, Neja M, Hopkins L, Dashti A, Jean S, Wood JS, Ehnert S, Liang S, Vanderford T, Tharp GK, Bosinger SE, Schauer AP, Mavigner M, Cottrell ML, Margolis D, Dunham RM, Chahroudi A. Bricker KM, et al. Among authors: liang s. J Virol. 2022 Apr 13;96(7):e0169921. doi: 10.1128/jvi.01699-21. Epub 2022 Mar 16. J Virol. 2022. PMID: 35293766 Free PMC article.
SMAC Mimetic Plus Triple-Combination Bispecific HIVxCD3 Retargeting Molecules in SHIV.C.CH505-Infected, Antiretroviral Therapy-Suppressed Rhesus Macaques.
Dashti A, Waller C, Mavigner M, Schoof N, Bar KJ, Shaw GM, Vanderford TH, Liang S, Lifson JD, Dunham RM, Ferrari G, Tuyishime M, Lam CK, Nordstrom JL, Margolis DM, Silvestri G, Chahroudi A. Dashti A, et al. Among authors: liang s. J Virol. 2020 Oct 14;94(21):e00793-20. doi: 10.1128/JVI.00793-20. Print 2020 Oct 14. J Virol. 2020. PMID: 32817214 Free PMC article.
CD8 lymphocyte depletion enhances the latency reversal activity of the SMAC mimetic AZD5582 in ART-suppressed SIV-infected rhesus macaques.
Mavigner M, Liao LE, Brooks AD, Ke R, Mattingly C, Schoof N, McBrien J, Carnathan D, Liang S, Vanderford TH, Paiardini M, Kulpa D, Lifson JD, Dunham RM, Easley KA, Margolis DM, Perelson AS, Silvestri G, Chahroudi A. Mavigner M, et al. Among authors: liang s. J Virol. 2021 Mar 25;95(8):e01429-20. doi: 10.1128/JVI.01429-20. Epub 2021 Feb 10. J Virol. 2021. PMID: 33568515 Free PMC article.
Dynamics and origin of rebound viremia in SHIV-infected infant macaques following interruption of long-term ART.
Obregon-Perko V, Bricker KM, Mensah G, Uddin F, Rotolo L, Vanover D, Desai Y, Santangelo PJ, Jean S, Wood JS, Connor-Stroud FC, Ehnert S, Berendam SJ, Liang S, Vanderford TH, Bar KJ, Shaw GM, Silvestri G, Kumar A, Fouda GG, Permar SR, Chahroudi A. Obregon-Perko V, et al. Among authors: liang s. JCI Insight. 2021 Dec 8;6(23):e152526. doi: 10.1172/jci.insight.152526. JCI Insight. 2021. PMID: 34699383 Free PMC article.
The lethal K18-hACE2 knock-in mouse model mimicking the severe pneumonia of COVID-19 is practicable for antiviral development.
Zhang Z, Zhou L, Liu Q, Zheng Y, Tan X, Huang Z, Guo M, Wang X, Chen X, Liang S, Li W, Song K, Yan K, Li J, Li Q, Zhang Y, Yang S, Cai Z, Dai M, Xian Q, Shi ZL, Xu K, Lan K, Chen Y. Zhang Z, et al. Among authors: liang s. Emerg Microbes Infect. 2024 May 16:2353302. doi: 10.1080/22221751.2024.2353302. Online ahead of print. Emerg Microbes Infect. 2024. PMID: 38753462
9,247 results