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Clofazimine broadly inhibits coronaviruses including SARS-CoV-2.
Yuan S, Yin X, Meng X, Chan JF, Ye ZW, Riva L, Pache L, Chan CC, Lai PM, Chan CC, Poon VK, Lee AC, Matsunaga N, Pu Y, Yuen CK, Cao J, Liang R, Tang K, Sheng L, Du Y, Xu W, Lau CY, Sit KY, Au WK, Wang R, Zhang YY, Tang YD, Clausen TM, Pihl J, Oh J, Sze KH, Zhang AJ, Chu H, Kok KH, Wang D, Cai XH, Esko JD, Hung IF, Li RA, Chen H, Sun H, Jin DY, Sun R, Chanda SK, Yuen KY. Yuan S, et al. Among authors: liang r. Nature. 2021 May;593(7859):418-423. doi: 10.1038/s41586-021-03431-4. Epub 2021 Mar 16. Nature. 2021. PMID: 33727703
Pathogenicity, transmissibility, and fitness of SARS-CoV-2 Omicron in Syrian hamsters.
Yuan S, Ye ZW, Liang R, Tang K, Zhang AJ, Lu G, Ong CP, Man Poon VK, Chan CC, Mok BW, Qin Z, Xie Y, Chu AW, Chan WM, Ip JD, Sun H, Tsang JO, Yuen TT, Chik KK, Chan CC, Cai JP, Luo C, Lu L, Yip CC, Chu H, To KK, Chen H, Jin DY, Yuen KY, Chan JF. Yuan S, et al. Among authors: liang r. Science. 2022 Jul 22;377(6604):428-433. doi: 10.1126/science.abn8939. Epub 2022 Jun 23. Science. 2022. PMID: 35737809 Free article.
The spike receptor-binding motif G496S substitution determines the replication fitness of SARS-CoV-2 Omicron sublineage.
Liang R, Ye ZW, Ong CP, Qin Z, Xie Y, Fan Y, Tang K, Poon VK, Chan CC, Yang X, Cao H, Wang K, Sun H, Hu B, Cai JP, Luo C, Chik KK, Chu H, Zheng Y, Yuen KY, Chan JF, Jin DY, Yuan S. Liang R, et al. Emerg Microbes Infect. 2022 Dec;11(1):2093-2101. doi: 10.1080/22221751.2022.2111977. Emerg Microbes Infect. 2022. PMID: 35943779 Free PMC article.
Simulation of the Clinical and Pathological Manifestations of Coronavirus Disease 2019 (COVID-19) in a Golden Syrian Hamster Model: Implications for Disease Pathogenesis and Transmissibility.
Chan JF, Zhang AJ, Yuan S, Poon VK, Chan CC, Lee AC, Chan WM, Fan Z, Tsoi HW, Wen L, Liang R, Cao J, Chen Y, Tang K, Luo C, Cai JP, Kok KH, Chu H, Chan KH, Sridhar S, Chen Z, Chen H, To KK, Yuen KY. Chan JF, et al. Among authors: liang r. Clin Infect Dis. 2020 Dec 3;71(9):2428-2446. doi: 10.1093/cid/ciaa325. Clin Infect Dis. 2020. PMID: 32215622 Free PMC article.
Surgical Mask Partition Reduces the Risk of Noncontact Transmission in a Golden Syrian Hamster Model for Coronavirus Disease 2019 (COVID-19).
Chan JF, Yuan S, Zhang AJ, Poon VK, Chan CC, Lee AC, Fan Z, Li C, Liang R, Cao J, Tang K, Luo C, Cheng VC, Cai JP, Chu H, Chan KH, To KK, Sridhar S, Yuen KY. Chan JF, et al. Among authors: liang r. Clin Infect Dis. 2020 Nov 19;71(16):2139-2149. doi: 10.1093/cid/ciaa644. Clin Infect Dis. 2020. PMID: 32472679 Free PMC article.
Discovery of the FDA-approved drugs bexarotene, cetilistat, diiodohydroxyquinoline, and abiraterone as potential COVID-19 treatments with a robust two-tier screening system.
Yuan S, Chan JFW, Chik KKH, Chan CCY, Tsang JOL, Liang R, Cao J, Tang K, Chen LL, Wen K, Cai JP, Ye ZW, Lu G, Chu H, Jin DY, Yuen KY. Yuan S, et al. Among authors: liang r. Pharmacol Res. 2020 Sep;159:104960. doi: 10.1016/j.phrs.2020.104960. Epub 2020 May 28. Pharmacol Res. 2020. PMID: 32473310 Free PMC article.
3,679 results