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Predicting continuous amyloid PET values with CSF and plasma Aβ42/Aβ40.
Wisch JK, Gordon BA, Boerwinkle AH, Luckett PH, Bollinger JG, Ovod V, Li Y, Henson RL, West T, Meyer MR, Kirmess KM, Benzinger TLS, Fagan AM, Morris JC, Bateman RJ, Ances BM, Schindler SE. Wisch JK, et al. Among authors: li y. Alzheimers Dement (Amst). 2023 Mar 2;15(1):e12405. doi: 10.1002/dad2.12405. eCollection 2023 Jan-Mar. Alzheimers Dement (Amst). 2023. PMID: 36874595 Free PMC article.
CSF tau phosphorylation occupancies at T217 and T205 represent improved biomarkers of amyloid and tau pathology in Alzheimer's disease.
Barthélemy NR, Saef B, Li Y, Gordon BA, He Y, Horie K, Stomrud E, Salvadó G, Janelidze S, Sato C, Ovod V, Henson RL, Fagan AM, Benzinger TLS, Xiong C, Morris JC, Hansson O, Bateman RJ, Schindler SE. Barthélemy NR, et al. Among authors: li y. Nat Aging. 2023 Apr;3(4):391-401. doi: 10.1038/s43587-023-00380-7. Epub 2023 Mar 13. Nat Aging. 2023. PMID: 37117788 Free PMC article.
Performance of the Lumipulse plasma Aβ42/40 and pTau181 immunoassays in the detection of amyloid pathology.
Figdore DJ, Wiste HJ, Bornhorst JA, Bateman RJ, Li Y, Graff-Radford J, Knopman DS, Vemuri P, Lowe VJ, Jr CRJ, Petersen RC, Algeciras-Schimnich A. Figdore DJ, et al. Among authors: li y. Alzheimers Dement (Amst). 2024 Jan 31;16(1):e12545. doi: 10.1002/dad2.12545. eCollection 2024 Jan-Mar. Alzheimers Dement (Amst). 2024. PMID: 38304322 Free PMC article.
Longitudinal head-to-head comparison of 11C-PiB and 18F-florbetapir PET in a Phase 2/3 clinical trial of anti-amyloid-β monoclonal antibodies in dominantly inherited Alzheimer's disease.
Chen CD, McCullough A, Gordon B, Joseph-Mathurin N, Flores S, McKay NS, Hobbs DA, Hornbeck R, Fagan AM, Cruchaga C, Goate AM, Perrin RJ, Wang G, Li Y, Shi X, Xiong C, Pontecorvo MJ, Klein G, Su Y, Klunk WE, Jack C, Koeppe R, Snider BJ, Berman SB, Roberson ED, Brosch J, Surti G, Jiménez-Velázquez IZ, Galasko D, Honig LS, Brooks WS, Clarnette R, Wallon D, Dubois B, Pariente J, Pasquier F, Sanchez-Valle R, Shcherbinin S, Higgins I, Tunali I, Masters CL, van Dyck CH, Masellis M, Hsiung R, Gauthier S, Salloway S, Clifford DB, Mills S, Supnet-Bell C, McDade E, Bateman RJ, Benzinger TLS; DIAN-TU Study Team. Chen CD, et al. Among authors: li y. Eur J Nucl Med Mol Imaging. 2023 Jul;50(9):2669-2682. doi: 10.1007/s00259-023-06209-0. Epub 2023 Apr 5. Eur J Nucl Med Mol Imaging. 2023. PMID: 37017737 Free PMC article. Clinical Trial.
Highly accurate blood test for Alzheimer's disease is similar or superior to clinical cerebrospinal fluid tests.
Barthélemy NR, Salvadó G, Schindler SE, He Y, Janelidze S, Collij LE, Saef B, Henson RL, Chen CD, Gordon BA, Li Y, La Joie R, Benzinger TLS, Morris JC, Mattsson-Carlgren N, Palmqvist S, Ossenkoppele R, Rabinovici GD, Stomrud E, Bateman RJ, Hansson O. Barthélemy NR, et al. Among authors: li y. Nat Med. 2024 Apr;30(4):1085-1095. doi: 10.1038/s41591-024-02869-z. Epub 2024 Feb 21. Nat Med. 2024. PMID: 38382645 Free PMC article.
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