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Efficacy and Safety of Adintrevimab (ADG20) for the Treatment of High-Risk Ambulatory Patients With Mild or Moderate Coronavirus Disease 2019: Results From a Phase 2/3, Randomized, Placebo-Controlled Trial (STAMP) Conducted During Delta Predominance and Early Emergence of Omicron.
Ison MG, Popejoy M, Evgeniev N, Tzekova M, Mahoney K, Betancourt N, Li Y, Gupta D, Narayan K, Hershberger E, Connolly LE, Yalcin I, Das AF, Genge J, Smith M, Campanaro E, Hawn P, Schmidt P; STAMP Study Group. Ison MG, et al. Among authors: li y. Open Forum Infect Dis. 2023 May 24;10(6):ofad279. doi: 10.1093/ofid/ofad279. eCollection 2023 Jun. Open Forum Infect Dis. 2023. PMID: 37351456 Free PMC article.
Safety, Pharmacokinetics, Serum Neutralizing Titers, and Immunogenicity of Adintrevimab, a Monoclonal Antibody Targeting SARS-CoV-2: A Randomized, Double-Blind, Placebo-Controlled, Phase 1 Dose-escalation Study in Healthy Adults.
Schmidt P, Gong J, Narayan K, Gupta D, Engler F, Li Y, Copans A, Campanaro E. Schmidt P, et al. Among authors: li y. Infect Dis Ther. 2023 May;12(5):1365-1377. doi: 10.1007/s40121-023-00794-1. Epub 2023 Apr 25. Infect Dis Ther. 2023. PMID: 37185797 Free PMC article.
Antibody-mediated protection against symptomatic COVID-19 can be achieved at low serum neutralizing titers.
Schmidt P, Narayan K, Li Y, Kaku CI, Brown ME, Champney E, Geoghegan JC, Vásquez M, Krauland EM, Yockachonis T, Bai S, Gunn BM, Cammarata A, Rubino CM, Ambrose P, Walker LM. Schmidt P, et al. Among authors: li y. Sci Transl Med. 2023 Mar 22;15(688):eadg2783. doi: 10.1126/scitranslmed.adg2783. Epub 2023 Mar 22. Sci Transl Med. 2023. PMID: 36947596 Free article.
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