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A stromal Integrated Stress Response activates perivascular cancer-associated fibroblasts to drive angiogenesis and tumour progression.
Verginadis II, Avgousti H, Monslow J, Skoufos G, Chinga F, Kim K, Leli NM, Karagounis IV, Bell BI, Velalopoulou A, Salinas CS, Wu VS, Li Y, Ye J, Scott DA, Osterman AL, Sengupta A, Weljie A, Huang M, Zhang D, Fan Y, Radaelli E, Tobias JW, Rambow F, Karras P, Marine JC, Xu X, Hatzigeorgiou AG, Ryeom S, Diehl JA, Fuchs SY, Puré E, Koumenis C. Verginadis II, et al. Among authors: li y. Nat Cell Biol. 2022 Jun;24(6):940-953. doi: 10.1038/s41556-022-00918-8. Epub 2022 Jun 2. Nat Cell Biol. 2022. PMID: 35654839 Free PMC article.
p53 Suppresses Metabolic Stress-Induced Ferroptosis in Cancer Cells.
Tarangelo A, Magtanong L, Bieging-Rolett KT, Li Y, Ye J, Attardi LD, Dixon SJ. Tarangelo A, et al. Among authors: li y. Cell Rep. 2018 Jan 16;22(3):569-575. doi: 10.1016/j.celrep.2017.12.077. Cell Rep. 2018. PMID: 29346757 Free PMC article.
Serine starvation silences estrogen receptor signaling through histone hypoacetylation.
Li AM, He B, Karagiannis D, Li Y, Jiang H, Srinivasan P, Ramirez Y, Zhou MN, Curtis C, Gruber JJ, Lu C, Rankin EB, Ye J. Li AM, et al. Among authors: li y. Proc Natl Acad Sci U S A. 2023 Sep 19;120(38):e2302489120. doi: 10.1073/pnas.2302489120. Epub 2023 Sep 11. Proc Natl Acad Sci U S A. 2023. PMID: 37695911 Free PMC article.
Metabolic Profiling Reveals a Dependency of Human Metastatic Breast Cancer on Mitochondrial Serine and One-Carbon Unit Metabolism.
Li AM, Ducker GS, Li Y, Seoane JA, Xiao Y, Melemenidis S, Zhou Y, Liu L, Vanharanta S, Graves EE, Rankin EB, Curtis C, Massagué J, Rabinowitz JD, Thompson CB, Ye J. Li AM, et al. Among authors: li y. Mol Cancer Res. 2020 Apr;18(4):599-611. doi: 10.1158/1541-7786.MCR-19-0606. Epub 2020 Jan 15. Mol Cancer Res. 2020. PMID: 31941752 Free PMC article.
A STING-activating nanovaccine for cancer immunotherapy.
Luo M, Wang H, Wang Z, Cai H, Lu Z, Li Y, Du M, Huang G, Wang C, Chen X, Porembka MR, Lea J, Frankel AE, Fu YX, Chen ZJ, Gao J. Luo M, et al. Among authors: li y. Nat Nanotechnol. 2017 Jul;12(7):648-654. doi: 10.1038/nnano.2017.52. Epub 2017 Apr 24. Nat Nanotechnol. 2017. PMID: 28436963 Free PMC article.
The m6A RNA demethylase FTO is a HIF-independent synthetic lethal partner with the VHL tumor suppressor.
Xiao Y, Thakkar KN, Zhao H, Broughton J, Li Y, Seoane JA, Diep AN, Metzner TJ, von Eyben R, Dill DL, Brooks JD, Curtis C, Leppert JT, Ye J, Peehl DM, Giaccia AJ, Sinha S, Rankin EB. Xiao Y, et al. Among authors: li y. Proc Natl Acad Sci U S A. 2020 Sep 1;117(35):21441-21449. doi: 10.1073/pnas.2000516117. Epub 2020 Aug 19. Proc Natl Acad Sci U S A. 2020. PMID: 32817424 Free PMC article.
Novel Aza-podophyllotoxin derivative induces oxidative phosphorylation and cell death via AMPK activation in triple-negative breast cancer.
Tailor D, Going CC, Resendez A, Kumar V, Nambiar DK, Li Y, Dheeraj A, LaGory EL, Ghoochani A, Birk AM, Stoyanova T, Ye J, Giaccia AJ, Le QT, Singh RP, Sledge GW, Pitteri SJ, Malhotra SV. Tailor D, et al. Among authors: li y. Br J Cancer. 2021 Feb;124(3):604-615. doi: 10.1038/s41416-020-01137-4. Epub 2020 Nov 3. Br J Cancer. 2021. PMID: 33139797 Free PMC article.
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