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Impact of Bronchiectasis on COPD Severity and Alpha-1 Antitrypsin Deficiency as a Risk Factor in Individuals with a Heavy Smoking History.
Izquierdo M, Marion CR, Genese F, Newell JD, O'Neal WK, Li X, Hawkins GA, Barjaktarevic I, Barr RG, Christenson S, Cooper CB, Couper D, Curtis J, Han MK, Hansel NN, Kanner RE, Martinez FJ, Paine R 3rd, Tejwani V, Woodruff PG, Zein JG, Hoffman EA, Peters SP, Meyers DA, Bleecker ER, Ortega VE; SubPopulations and InteRmediate Outcome Measures In COPD Study (SPIROMICS) investigators. Izquierdo M, et al. Among authors: li x. Chronic Obstr Pulm Dis. 2023 Jul 26;10(3):199-210. doi: 10.15326/jcopdf.2023.0388. Chronic Obstr Pulm Dis. 2023. PMID: 37199731 Free PMC article.
Identification of asthma phenotypes using cluster analysis in the Severe Asthma Research Program.
Moore WC, Meyers DA, Wenzel SE, Teague WG, Li H, Li X, D'Agostino R Jr, Castro M, Curran-Everett D, Fitzpatrick AM, Gaston B, Jarjour NN, Sorkness R, Calhoun WJ, Chung KF, Comhair SA, Dweik RA, Israel E, Peters SP, Busse WW, Erzurum SC, Bleecker ER; National Heart, Lung, and Blood Institute's Severe Asthma Research Program. Moore WC, et al. Among authors: li h, li x. Am J Respir Crit Care Med. 2010 Feb 15;181(4):315-23. doi: 10.1164/rccm.200906-0896OC. Epub 2009 Nov 5. Am J Respir Crit Care Med. 2010. PMID: 19892860 Free PMC article.
Importance of hedgehog interacting protein and other lung function genes in asthma.
Li X, Howard TD, Moore WC, Ampleford EJ, Li H, Busse WW, Calhoun WJ, Castro M, Chung KF, Erzurum SC, Fitzpatrick AM, Gaston B, Israel E, Jarjour NN, Teague WG, Wenzel SE, Peters SP, Hawkins GA, Bleecker ER, Meyers DA. Li X, et al. Among authors: li h. J Allergy Clin Immunol. 2011 Jun;127(6):1457-65. doi: 10.1016/j.jaci.2011.01.056. Epub 2011 Mar 12. J Allergy Clin Immunol. 2011. PMID: 21397937 Free PMC article.
The IL6R variation Asp(358)Ala is a potential modifier of lung function in subjects with asthma.
Hawkins GA, Robinson MB, Hastie AT, Li X, Li H, Moore WC, Howard TD, Busse WW, Erzurum SC, Wenzel SE, Peters SP, Meyers DA, Bleecker ER; National Heart, Lung, and Blood Institute–sponsored Severe Asthma Research Program (SARP). Hawkins GA, et al. Among authors: li x, li h. J Allergy Clin Immunol. 2012 Aug;130(2):510-5.e1. doi: 10.1016/j.jaci.2012.03.018. Epub 2012 May 1. J Allergy Clin Immunol. 2012. PMID: 22554704 Free PMC article.
Genome-wide association studies of asthma indicate opposite immunopathogenesis direction from autoimmune diseases.
Li X, Ampleford EJ, Howard TD, Moore WC, Torgerson DG, Li H, Busse WW, Castro M, Erzurum SC, Israel E, Nicolae DL, Ober C, Wenzel SE, Hawkins GA, Bleecker ER, Meyers DA. Li X, et al. Among authors: li h. J Allergy Clin Immunol. 2012 Oct;130(4):861-8.e7. doi: 10.1016/j.jaci.2012.04.041. Epub 2012 Jun 12. J Allergy Clin Immunol. 2012. PMID: 22694930 Free PMC article.
Genetics of asthma susceptibility and severity.
Slager RE, Hawkins GA, Li X, Postma DS, Meyers DA, Bleecker ER. Slager RE, et al. Among authors: li x. Clin Chest Med. 2012 Sep;33(3):431-43. doi: 10.1016/j.ccm.2012.05.005. Epub 2012 Jul 7. Clin Chest Med. 2012. PMID: 22929093 Free PMC article. Review.
Genome-wide association study identifies TH1 pathway genes associated with lung function in asthmatic patients.
Li X, Hawkins GA, Ampleford EJ, Moore WC, Li H, Hastie AT, Howard TD, Boushey HA, Busse WW, Calhoun WJ, Castro M, Erzurum SC, Israel E, Lemanske RF Jr, Szefler SJ, Wasserman SI, Wenzel SE, Peters SP, Meyers DA, Bleecker ER. Li X, et al. Among authors: li h. J Allergy Clin Immunol. 2013 Aug;132(2):313-20.e15. doi: 10.1016/j.jaci.2013.01.051. Epub 2013 Mar 28. J Allergy Clin Immunol. 2013. PMID: 23541324 Free PMC article.
Clinical heterogeneity in the severe asthma research program.
Moore WC, Fitzpatrick AM, Li X, Hastie AT, Li H, Meyers DA, Bleecker ER. Moore WC, et al. Among authors: li x, li h. Ann Am Thorac Soc. 2013 Dec;10 Suppl(Suppl):S118-24. doi: 10.1513/AnnalsATS.201309-307AW. Ann Am Thorac Soc. 2013. PMID: 24313761 Free PMC article.
Sputum neutrophil counts are associated with more severe asthma phenotypes using cluster analysis.
Moore WC, Hastie AT, Li X, Li H, Busse WW, Jarjour NN, Wenzel SE, Peters SP, Meyers DA, Bleecker ER; National Heart, Lung, and Blood Institute's Severe Asthma Research Program. Moore WC, et al. Among authors: li x, li h. J Allergy Clin Immunol. 2014 Jun;133(6):1557-63.e5. doi: 10.1016/j.jaci.2013.10.011. Epub 2013 Dec 9. J Allergy Clin Immunol. 2014. PMID: 24332216 Free PMC article.
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