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Patient-derived models recapitulate heterogeneity of molecular signatures and drug response in pediatric high-grade glioma.
He C, Xu K, Zhu X, Dunphy PS, Gudenas B, Lin W, Twarog N, Hover LD, Kwon CH, Kasper LH, Zhang J, Li X, Dalton J, Jonchere B, Mercer KS, Currier DG, Caufield W, Wang Y, Xie J, Broniscer A, Wetmore C, Upadhyaya SA, Qaddoumi I, Klimo P, Boop F, Gajjar A, Zhang J, Orr BA, Robinson GW, Monje M, Freeman Iii BB, Roussel MF, Northcott PA, Chen T, Rankovic Z, Wu G, Chiang J, Tinkle CL, Shelat AA, Baker SJ. He C, et al. Among authors: li x. Nat Commun. 2021 Jul 2;12(1):4089. doi: 10.1038/s41467-021-24168-8. Nat Commun. 2021. PMID: 34215733 Free PMC article.
Phase I study using crenolanib to target PDGFR kinase in children and young adults with newly diagnosed DIPG or recurrent high-grade glioma, including DIPG.
Tinkle CL, Broniscer A, Chiang J, Campagne O, Huang J, Orr BA, Li X, Patay Z, Zhang J, Baker SJ, Merchant TE, Jain V, Onar-Thomas A, Stewart CF, Wetmore C, Gajjar A. Tinkle CL, et al. Among authors: li x. Neurooncol Adv. 2021 Dec 1;3(1):vdab179. doi: 10.1093/noajnl/vdab179. eCollection 2021 Jan-Dec. Neurooncol Adv. 2021. PMID: 34993482 Free PMC article.
Defining Optimal Target Volumes of Conformal Radiation Therapy for Diffuse Intrinsic Pontine Glioma.
Tinkle CL, Simone B, Chiang J, Li X, Campbell K, Han Y, Li Y, Hover LD, Molitoris JK, Becksfort J, Lucas JT Jr, Patay Z, Baker SJ, Broniscer A, Merchant TE. Tinkle CL, et al. Among authors: li y, li x. Int J Radiat Oncol Biol Phys. 2020 Mar 15;106(4):838-847. doi: 10.1016/j.ijrobp.2019.11.020. Epub 2019 Nov 27. Int J Radiat Oncol Biol Phys. 2020. PMID: 31785339 Free PMC article.
168,316 results
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