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Discovery of ANA975: an oral prodrug of the TLR-7 agonist isatoribine.
Xiang AX, Webber SE, Kerr BM, Rueden EJ, Lennox JR, Haley GJ, Wang T, Ng JS, Herbert MR, Clark DL, Banh VN, Li W, Fletcher SP, Steffy KR, Bartkowski DM, Kirkovsky LI, Bauman LA, Averett DR. Xiang AX, et al. Among authors: li w. Nucleosides Nucleotides Nucleic Acids. 2007;26(6-7):635-40. doi: 10.1080/15257770701490472. Nucleosides Nucleotides Nucleic Acids. 2007. PMID: 18066870 Clinical Trial.
The pharmacology of endosomal TLR agonists in viral disease.
Averett DR, Fletcher SP, Li W, Webber SE, Appleman JR. Averett DR, et al. Among authors: li w. Biochem Soc Trans. 2007 Dec;35(Pt 6):1468-72. doi: 10.1042/BST0351468. Biochem Soc Trans. 2007. PMID: 18031247 Review.
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