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Whole-genome sequencing and comprehensive molecular profiling identify new driver mutations in gastric cancer.
Wang K, Yuen ST, Xu J, Lee SP, Yan HH, Shi ST, Siu HC, Deng S, Chu KM, Law S, Chan KH, Chan AS, Tsui WY, Ho SL, Chan AK, Man JL, Foglizzo V, Ng MK, Chan AS, Ching YP, Cheng GH, Xie T, Fernandez J, Li VS, Clevers H, Rejto PA, Mao M, Leung SY. Wang K, et al. Among authors: li vs. Nat Genet. 2014 Jun;46(6):573-82. doi: 10.1038/ng.2983. Epub 2014 May 11. Nat Genet. 2014. PMID: 24816253
The kinase TNIK is an essential activator of Wnt target genes.
Mahmoudi T, Li VS, Ng SS, Taouatas N, Vries RG, Mohammed S, Heck AJ, Clevers H. Mahmoudi T, et al. Among authors: li vs. EMBO J. 2009 Nov 4;28(21):3329-40. doi: 10.1038/emboj.2009.285. Epub 2009 Oct 8. EMBO J. 2009. PMID: 19816403 Free PMC article.
Lgr5 homologues associate with Wnt receptors and mediate R-spondin signalling.
de Lau W, Barker N, Low TY, Koo BK, Li VS, Teunissen H, Kujala P, Haegebarth A, Peters PJ, van de Wetering M, Stange DE, van Es JE, Guardavaccaro D, Schasfoort RB, Mohri Y, Nishimori K, Mohammed S, Heck AJ, Clevers H. de Lau W, et al. Among authors: li vs. Nature. 2011 Jul 4;476(7360):293-7. doi: 10.1038/nature10337. Nature. 2011. PMID: 21727895
86 results