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The stress granule protein G3BP1 promotes pre-condensation of cGAS to allow rapid responses to DNA.
Zhao M, Xia T, Xing JQ, Yin LH, Li XW, Pan J, Liu JY, Sun LM, Wang M, Li T, Mao J, Han QY, Xue W, Cai H, Wang K, Xu X, Li T, He K, Wang N, Li AL, Zhou T, Zhang XM, Li WH, Li T. Zhao M, et al. Among authors: li xw, li t, li wh, li al. EMBO Rep. 2022 Jan 5;23(1):e53166. doi: 10.15252/embr.202153166. Epub 2021 Nov 15. EMBO Rep. 2022. PMID: 34779554 Free PMC article.
NEDD4 ubiquitinates TRAF3 to promote CD40-mediated AKT activation.
Fang DF, He K, Wang N, Sang ZH, Qiu X, Xu G, Jian Z, Liang B, Li T, Li HY, Li AL, Zhou T, Gong WL, Yang B, Karin M, Zhang XM, Li WH. Fang DF, et al. Among authors: li t, li hy, li wh, li al. Nat Commun. 2014 Jul 29;5:4513. doi: 10.1038/ncomms5513. Nat Commun. 2014. PMID: 25072696 Free article.
RNF4 negatively regulates NF-κB signaling by down-regulating TAB2.
Tan B, Mu R, Chang Y, Wang YB, Wu M, Tu HQ, Zhang YC, Guo SS, Qin XH, Li T, Li WH, Zhang XM, Li AL, Li HY. Tan B, et al. Among authors: li t, li wh, li hy, li al. FEBS Lett. 2015 Sep 14;589(19 Pt B):2850-8. doi: 10.1016/j.febslet.2015.07.051. Epub 2015 Aug 20. FEBS Lett. 2015. PMID: 26299341 Free article.
NLRP3 Phosphorylation Is an Essential Priming Event for Inflammasome Activation.
Song N, Liu ZS, Xue W, Bai ZF, Wang QY, Dai J, Liu X, Huang YJ, Cai H, Zhan XY, Han QY, Wang H, Chen Y, Li HY, Li AL, Zhang XM, Zhou T, Li T. Song N, et al. Among authors: li t, li hy, li al. Mol Cell. 2017 Oct 5;68(1):185-197.e6. doi: 10.1016/j.molcel.2017.08.017. Epub 2017 Sep 21. Mol Cell. 2017. PMID: 28943315 Free article.
G3BP1 promotes DNA binding and activation of cGAS.
Liu ZS, Cai H, Xue W, Wang M, Xia T, Li WJ, Xing JQ, Zhao M, Huang YJ, Chen S, Wu SM, Wang X, Liu X, Pang X, Zhang ZY, Li T, Dai J, Dong F, Xia Q, Li AL, Zhou T, Liu ZG, Zhang XM, Li T. Liu ZS, et al. Among authors: li t, li wj, li al. Nat Immunol. 2019 Jan;20(1):18-28. doi: 10.1038/s41590-018-0262-4. Epub 2018 Dec 3. Nat Immunol. 2019. PMID: 30510222 Free PMC article.
Acetylation Blocks cGAS Activity and Inhibits Self-DNA-Induced Autoimmunity.
Dai J, Huang YJ, He X, Zhao M, Wang X, Liu ZS, Xue W, Cai H, Zhan XY, Huang SY, He K, Wang H, Wang N, Sang Z, Li T, Han QY, Mao J, Diao X, Song N, Chen Y, Li WH, Man JH, Li AL, Zhou T, Liu ZG, Zhang XM, Li T. Dai J, et al. Among authors: li t, li wh, li al. Cell. 2019 Mar 7;176(6):1447-1460.e14. doi: 10.1016/j.cell.2019.01.016. Epub 2019 Feb 21. Cell. 2019. PMID: 30799039 Free PMC article.
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