Li T - Search Results

1

Autophagy induction via STING trafficking is a primordial function of the cGAS pathway.

Gui X, Yang H, Li T, Tan X, Shi P, Li M, Du F, Chen ZJ. Gui X, et al. Among authors: li t, li m. Nature. 2019 Mar;567(7747):262-266. doi: 10.1038/s41586-019-1006-9. Epub 2019 Mar 6. Nature. 2019. PMID: 30842662 Free PMC article.

2

Apoptotic caspases prevent the induction of type I interferons by mitochondrial DNA.

Rongvaux A, Jackson R, Harman CC, Li T, West AP, de Zoete MR, Wu Y, Yordy B, Lakhani SA, Kuan CY, Taniguchi T, Shadel GS, Chen ZJ, Iwasaki A, Flavell RA. Rongvaux A, et al. Among authors: li t. Cell. 2014 Dec 18;159(7):1563-77. doi: 10.1016/j.cell.2014.11.037. Cell. 2014. PMID: 25525875 Free PMC article.

3

Phosphorylation of innate immune adaptor proteins MAVS, STING, and TRIF induces IRF3 activation.

Liu S, Cai X, Wu J, Cong Q, Chen X, Li T, Du F, Ren J, Wu YT, Grishin NV, Chen ZJ. Liu S, et al. Among authors: li t. Science. 2015 Mar 13;347(6227):aaa2630. doi: 10.1126/science.aaa2630. Epub 2015 Jan 29. Science. 2015. PMID: 25636800

4

Cyclic GMP-AMP Synthase Is an Innate Immune DNA Sensor for Mycobacterium tuberculosis.

Collins AC, Cai H, Li T, Franco LH, Li XD, Nair VR, Scharn CR, Stamm CE, Levine B, Chen ZJ, Shiloh MU. Collins AC, et al. Among authors: li t, li xd. Cell Host Microbe. 2015 Jun 10;17(6):820-8. doi: 10.1016/j.chom.2015.05.005. Epub 2015 Jun 2. Cell Host Microbe. 2015. PMID: 26048137 Free PMC article.

5

Activation of cyclic GMP-AMP synthase by self-DNA causes autoimmune diseases.

Gao D, Li T, Li XD, Chen X, Li QZ, Wight-Carter M, Chen ZJ. Gao D, et al. Among authors: li t, li xd, li qz. Proc Natl Acad Sci U S A. 2015 Oct 20;112(42):E5699-705. doi: 10.1073/pnas.1516465112. Epub 2015 Sep 14. Proc Natl Acad Sci U S A. 2015. PMID: 26371324 Free PMC article.

6

An Argonaute phosphorylation cycle promotes microRNA-mediated silencing.

Golden RJ, Chen B, Li T, Braun J, Manjunath H, Chen X, Wu J, Schmid V, Chang TC, Kopp F, Ramirez-Martinez A, Tagliabracci VS, Chen ZJ, Xie Y, Mendell JT. Golden RJ, et al. Among authors: li t. Nature. 2017 Feb 9;542(7640):197-202. doi: 10.1038/nature21025. Epub 2017 Jan 23. Nature. 2017. PMID: 28114302 Free PMC article.

7

Cytosolic DNA Sensing Promotes Macrophage Transformation and Governs Myocardial Ischemic Injury.

Cao DJ, Schiattarella GG, Villalobos E, Jiang N, May HI, Li T, Chen ZJ, Gillette TG, Hill JA. Cao DJ, et al. Among authors: li t. Circulation. 2018 Jun 12;137(24):2613-2634. doi: 10.1161/CIRCULATIONAHA.117.031046. Epub 2018 Feb 1. Circulation. 2018. PMID: 29437120 Free PMC article.

8

The cGAS-cGAMP-STING pathway connects DNA damage to inflammation, senescence, and cancer.

Li T, Chen ZJ. Li T, et al. J Exp Med. 2018 May 7;215(5):1287-1299. doi: 10.1084/jem.20180139. Epub 2018 Apr 5. J Exp Med. 2018. PMID: 29622565 Free PMC article. Review.

9

Phosphorylation and chromatin tethering prevent cGAS activation during mitosis.

Li T, Huang T, Du M, Chen X, Du F, Ren J, Chen ZJ. Li T, et al. Science. 2021 Mar 19;371(6535):eabc5386. doi: 10.1126/science.abc5386. Epub 2021 Feb 4. Science. 2021. PMID: 33542149 Free PMC article.

10

cGAS restricts colon cancer development by protecting intestinal barrier integrity.

Hu S, Fang Y, Chen X, Cheng T, Zhao M, Du M, Li T, Li M, Zeng Z, Wei Y, Gu Z, Zhang C, Sun L, Chen ZJ. Hu S, et al. Among authors: li t, li m. Proc Natl Acad Sci U S A. 2021 Jun 8;118(23):e2105747118. doi: 10.1073/pnas.2105747118. Proc Natl Acad Sci U S A. 2021. PMID: 34074794 Free PMC article.

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