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Pain-causing stinging nettle toxins target TMEM233 to modulate NaV1.7 function.
Jami S, Deuis JR, Klasfauseweh T, Cheng X, Kurdyukov S, Chung F, Okorokov AL, Li S, Zhang J, Cristofori-Armstrong B, Israel MR, Ju RJ, Robinson SD, Zhao P, Ragnarsson L, Andersson Å, Tran P, Schendel V, McMahon KL, Tran HNT, Chin YK, Zhu Y, Liu J, Crawford T, Purushothamvasan S, Habib AM, Andersson DA, Rash LD, Wood JN, Zhao J, Stehbens SJ, Mobli M, Leffler A, Jiang D, Cox JJ, Waxman SG, Dib-Hajj SD, Neely GG, Durek T, Vetter I. Jami S, et al. Among authors: li s. Nat Commun. 2023 Apr 28;14(1):2442. doi: 10.1038/s41467-023-37963-2. Nat Commun. 2023. PMID: 37117223 Free PMC article.
The Tarantula Venom Peptide Eo1a Binds to the Domain II S3-S4 Extracellular Loop of Voltage-Gated Sodium Channel NaV1.8 to Enhance Activation.
Deuis JR, Ragnarsson L, Robinson SD, Dekan Z, Chan L, Jin AH, Tran P, McMahon KL, Li S, Wood JN, Cox JJ, King GF, Herzig V, Vetter I. Deuis JR, et al. Among authors: li s. Front Pharmacol. 2022 Jan 14;12:789570. doi: 10.3389/fphar.2021.789570. eCollection 2021. Front Pharmacol. 2022. PMID: 35095499 Free PMC article.
Tools for analysis and conditional deletion of subsets of sensory neurons.
Santana-Varela S, Bogdanov YD, Gossage SJ, Okorokov AL, Li S, de Clauser L, Alves-Simoes M, Sexton JE, Iseppon F, Luiz AP, Zhao J, Wood JN, Cox JJ. Santana-Varela S, et al. Among authors: li s. Wellcome Open Res. 2021 Sep 30;6:250. doi: 10.12688/wellcomeopenres.17090.1. eCollection 2021. Wellcome Open Res. 2021. PMID: 35233469 Free PMC article.
Distinct transcriptional responses of mouse sensory neurons in models of human chronic pain conditions.
Bangash MA, Alles SRA, Santana-Varela S, Millet Q, Sikandar S, de Clauser L, Ter Heegde F, Habib AM, Pereira V, Sexton JE, Emery EC, Li S, Luiz AP, Erdos J, Gossage SJ, Zhao J, Cox JJ, Wood JN. Bangash MA, et al. Among authors: li s. Wellcome Open Res. 2018 Jun 25;3:78. doi: 10.12688/wellcomeopenres.14641.1. eCollection 2018. Wellcome Open Res. 2018. PMID: 30079380 Free PMC article.
A novel human pain insensitivity disorder caused by a point mutation in ZFHX2.
Habib AM, Matsuyama A, Okorokov AL, Santana-Varela S, Bras JT, Aloisi AM, Emery EC, Bogdanov YD, Follenfant M, Gossage SJ, Gras M, Humphrey J, Kolesnikov A, Le Cann K, Li S, Minett MS, Pereira V, Ponsolles C, Sikandar S, Torres JM, Yamaoka K, Zhao J, Komine Y, Yamamori T, Maniatis N, Panov KI, Houlden H, Ramirez JD, Bennett DLH, Marsili L, Bachiocco V, Wood JN, Cox JJ. Habib AM, et al. Among authors: li s. Brain. 2018 Feb 1;141(2):365-376. doi: 10.1093/brain/awx326. Brain. 2018. PMID: 29253101 Free PMC article.
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