Li S - Search Results

1

Comparative Oncology Assessment of a Novel Inhibitor of Valosin-Containing Protein in Tumor-Bearing Dogs.

LeBlanc AK, Mazcko CN, Fan TM, Vail DM, Flesner BK, Bryan JN, Li S, Wang F, Harris S, Vargas JD, Govindharajulu JP, Jaganathan S, Tomaino F, Srivastava AK, Chou TF, Stott GM, Covey JM, Mroczkowski B, Doroshow JH. LeBlanc AK, et al. Among authors: li s. Mol Cancer Ther. 2022 Oct 7;21(10):1510-1523. doi: 10.1158/1535-7163.MCT-22-0167. Mol Cancer Ther. 2022. PMID: 35876604 Free PMC article.

2

Evaluating p97 Inhibitor Analogues for Potency against p97-p37 and p97-Npl4-Ufd1 Complexes.

Gui L, Zhang X, Li K, Frankowski KJ, Li S, Wong DE, Moen DR, Porubsky PR, Lin HJ, Schoenen FJ, Chou TF. Gui L, et al. Among authors: li s, li k. ChemMedChem. 2016 May 6;11(9):953-7. doi: 10.1002/cmdc.201600036. Epub 2016 Apr 4. ChemMedChem. 2016. PMID: 27043824 Free PMC article.

3

Optimization of Phenyl Indole Inhibitors of the AAA+ ATPase p97.

LaPorte MG, Burnett JC, Colombo R, Bulfer SL, Alverez C, Chou TF, Neitz RJ, Green N, Moore WJ, Yue Z, Li S, Arkin MR, Wipf P, Huryn DM. LaPorte MG, et al. Among authors: li s. ACS Med Chem Lett. 2018 Sep 18;9(11):1075-1081. doi: 10.1021/acsmedchemlett.8b00372. eCollection 2018 Nov 8. ACS Med Chem Lett. 2018. PMID: 30429948 Free PMC article.

4

Allosteric p97 Inhibitors Can Overcome Resistance to ATP-Competitive p97 Inhibitors for Potential Anticancer Therapy.

Wang F, Li S, Gan T, Stott GM, Flint A, Chou TF. Wang F, et al. Among authors: li s. ChemMedChem. 2020 Apr 20;15(8):685-694. doi: 10.1002/cmdc.201900722. Epub 2020 Mar 23. ChemMedChem. 2020. PMID: 32162487 Free PMC article.

5

Enzyme Replacement Therapy for Mucopolysaccharidosis IIID using Recombinant Human α-N-Acetylglucosamine-6-Sulfatase in Neonatal Mice.

Wang F, Moen DR, Sauni C, Kan SH, Li S, Le SQ, Lomenick B, Zhang X, Ekins S, Singamsetty S, Wood J, Dickson PI, Chou TF. Wang F, et al. Among authors: li s. Mol Pharm. 2021 Jan 4;18(1):214-227. doi: 10.1021/acs.molpharmaceut.0c00831. Epub 2020 Dec 15. Mol Pharm. 2021. PMID: 33320673 Free PMC article.

6

A covalent p97/VCP ATPase inhibitor can overcome resistance to CB-5083 and NMS-873 in colorectal cancer cells.

Zhang G, Li S, Wang F, Jones AC, Goldberg AFG, Lin B, Virgil S, Stoltz BM, Deshaies RJ, Chou TF. Zhang G, et al. Among authors: li s. Eur J Med Chem. 2021 Mar 5;213:113148. doi: 10.1016/j.ejmech.2020.113148. Epub 2021 Jan 2. Eur J Med Chem. 2021. PMID: 33476933 Free PMC article.

7

AAA ATPases as therapeutic targets: Structure, functions, and small-molecule inhibitors.

Zhang G, Li S, Cheng KW, Chou TF. Zhang G, et al. Among authors: li s. Eur J Med Chem. 2021 Jul 5;219:113446. doi: 10.1016/j.ejmech.2021.113446. Epub 2021 Apr 10. Eur J Med Chem. 2021. PMID: 33873056 Free PMC article. Review.

8

Neuronal VCP loss of function recapitulates FTLD-TDP pathology.

Wani A, Zhu J, Ulrich JD, Eteleeb A, Sauerbeck AD, Reitz SJ, Arhzaouy K, Ikenaga C, Yuede CM, Pittman SK, Wang F, Li S, Benitez BA, Cruchaga C, Kummer TT, Harari O, Chou TF, Schröder R, Clemen CS, Weihl CC. Wani A, et al. Among authors: li s. Cell Rep. 2021 Jul 20;36(3):109399. doi: 10.1016/j.celrep.2021.109399. Cell Rep. 2021. PMID: 34289347 Free PMC article.

9

Structural and Functional Analysis of Disease-Linked p97 ATPase Mutant Complexes.

Nandi P, Li S, Columbres RCA, Wang F, Williams DR, Poh YP, Chou TF, Chiu PL. Nandi P, et al. Among authors: li s. Int J Mol Sci. 2021 Jul 28;22(15):8079. doi: 10.3390/ijms22158079. Int J Mol Sci. 2021. PMID: 34360842 Free PMC article.

10

Conserved L464 in p97 D1-D2 linker is critical for p97 cofactor regulated ATPase activity.

Zhang X, Gui L, Li S, Nandi P, Columbres RC, Wong DE, Moen DR, Lin HJ, Chiu PL, Chou TF. Zhang X, et al. Among authors: li s. Biochem J. 2021 Sep 17;478(17):3185-3204. doi: 10.1042/BCJ20210288. Biochem J. 2021. PMID: 34405853 Free PMC article.

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